NCT05599139Recruiting
Iodine Uptake After a Low Iodine Diet
The Uptake of Radioactive Iodine Before and After a Low Iodine Diet in Patients With Differentiated Thyroid Carcinoma
Source: ClinicalTrials.gov · Last updated 6 Feb 2026
Brief summary (registry, in English)
The goal of this clinical trial is to compare the difference in thyroid uptake of a low dose radioactive iodine (10 MBq 123-I or 37 MBq 123-I) in athyreotic patients with differentiated thyroid carcinoma before and after a low iodine diet (LID) of 7 days. The main question it aims to answer is: • What is the difference in iodine uptake before and after a LID of 7 days? Uptake of a low dose of 123-iodine will be measured in participants before and after a low iodine diet of 7 days. Researchers will compare the uptake (%) before and after the LID.
- Status (registry)
- Recruiting
- Study type
- Interventional
- Enrollment
- 25 (estimated)
- First submitted
- 25 Oct 2022
- Start date
- 22 Feb 2023
- Primary completion date
- 30 Mar 2026
- Lead sponsor
- University Medical Center Groningen
- Diseases
- Thyroid cancer
- NCT number
- NCT05599139
What you commit to
- Study type: Interventional
- Planned participants: 25
- From 22 Feb 2023 to the primary completion date, 30 Mar 2026
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Patients receiving iodinated contrast \< 3 months before the LID
- Patients prepared for ablation therapy with rhTSH
Lab values
- Renal impairment, EGFR \<30ml/min/1,73m2
Age
- Age \< 18 years
Other
- Patients using amiodarone
- Pregnancy
Who the study is looking for
- Patients, men and women above the age of 18 years, have to be diagnosed with DTC and have to follow a LID prior to the 131I ablation therapy according to the Dutch DTC guideline
- Patients have to be fit to adhere to the study protocol
- Patients have to be able to read and understand the Dutch language
Age in the registry: 18 years to 75 years · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Save your city in your profile to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| UMCG Coordinator of this site? Confirm its status | Groningen | Netherlands | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.