NCT05613062CompletedPhase 1/2
Modified Huang-Lian-Jie-Du Decoction (MHLJDD) for Atopic Dermatitis in Children
A Randomized Placebo-Controlled Pilot Study of an Herbal Formula Modified Huang-Lian-Jie-Du Decoction (MHLJDD) for Atopic Dermatitis in Children
Source: ClinicalTrials.gov · Last updated 27 Jul 2026
Brief summary (registry, in English)
The study aims to evaluate the clinical efficacy of Chinese medicine (CM) for the treatment of subacute and chronic Atopic Dermatitis (AD) patients when compared to the placebo control by examining the clinical symptoms.
- Status (registry)
- Completed
- Phase (registry)
- Phase 1/2
- Study type
- Interventional
- Enrollment
- 20 (actual)
- First submitted
- 29 Sept 2022
- Start date
- 11 Apr 2023
- Primary completion date
- 27 Aug 2024
- Lead sponsor
- Chinese University of Hong Kong
- Diseases
- Atopic dermatitis (eczema)
- NCT number
- NCT05613062
What you commit to
- Study type: Interventional · Phase 1/2
- Participants enrolled: 20
- From 11 Apr 2023 to the primary completion date, 27 Aug 2024
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study design.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Having used oral corticosteroids, oral antibiotics, other immunosuppressive or any preparation of oral herbal medicines for the treatment of AD in the past month;
Other illness
- History of allergy to Chinese medicines;
- AD with Yang deficiency in syndrome differentiation, such as pale looking, always feeling cold, fatigue, chronic diarrhea with loose stool, urinary disorders such as urinary difficulty, excessive urination or incontinence
- Known overt bacterial infections in the skin;
- Known severe medical conditions, such as cardiovascular, liver or renal dysfunction or Diabetes Mellitus;
- Having been diagnosed with scabies, allergic contact dermatitis, seborrheic dermatitis or psoriasis;
Lab values
- Has taken anti-coagulant or anti-platelet drugs in the past month;
- Known history of glucose-6-phosphate dehydrogenase (G6PD) deficiency.
Other
- Known pregnancy;
- Has taken any probiotics, prebiotics in the last month; and
Who the study is looking for
- Age of 4 to 17 (Chinese only);
- With EASI ≥ 10;
- Subacute and chronic atopic dermatitis presenting with dry, scaly, erythematous papules and plaques; and
- Provide a written informed consent form (signed by one of their parents)
Age in the registry: 4 years to 17 years · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Save your city in your profile to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| School of Chinese Medicine Coordinator of this site? Confirm its status | Hong Kong | Hong Kong | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.