NCT05613647Active, not recruiting
Concordance Study of Therapeutic Decision-making in Patients With Shock Based on Hemodynamic Monitoring
Concordance Study of Therapeutic Decision-making in Patients With Acute Circulatory Failure Between Cardiac Output Monitoring by Transthoracic Echocardiography and by Transpulmonary Thermodilution : PICC-ECHO Study
Source: ClinicalTrials.gov · Last updated 15 Jun 2025
Brief summary (registry, in English)
Shock is a serious complication corresponding to acute circulatory failure resulting in multiorgan failure and death. In order to improve cellular oxygen utilization, several therapies can be used. To select one of them, the monitoring of cardiac output is helpful. However, there are several methods used in current practice in intensive care for evaluating hemodynamic. Currently, in patients with acute circulatory failure, no study has compared the concordance of therapeutic decision-making based on transpulmonary thermodilution or transthoracic echocardiography. The objective of the PICC-ECHO study is thus to assess the concordance of therapeutic decision-making by several experts, based on data from transpulmonary thermodilution or transthoracic echocardiography. Indeed, the investigators hypothesize that performing hemodynamic monitoring based on transpulmonary thermodilution or transthoracic echocardiography does not lead to the same therapeutic management in patients in shock.
- Status (registry)
- Active, not recruiting
- Study type
- Observational
- Enrollment
- 15 (estimated)
- First submitted
- 30 Oct 2022
- Start date
- 13 Dec 2022
- Primary completion date
- 31 Dec 2025
- Lead sponsor
- University Hospital, Angers
- NCT number
- NCT05613647
What you commit to
- Study type: Observational
- Planned participants: 15
- From 13 Dec 2022 to the primary completion date, 31 Dec 2025
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- a relative who has received the information, if the patient's condition does not allow it, and who objects to the participation of his or her relative in the research;
Other illness
- patient with acute pulmonary heart on TTE (defined as a LV-to-VG ratio \> 0.6 associated with a paradoxical interventricular septum);
Other
- patient objecting to participation in the research;
- persons protected by law.
Who the study is looking for
- adult patient, hospitalized in the Intensive Care Medicine, CHU of Angers;
- patient requiring a hemodynamic evaluation because of an acute circulatory insufficiency defined by : arterial hypotension requiring vasopressor amines, with clinical signs (mottling, encephalopathy, oliguria \> 2h) and/or biological signs (pH \<7.38; lactate \> 2 mmol/L) of tissue hypoperfusion;
- patient monitored by transpulmonary thermodilution with pulse wave contour measurement (PiCCO) as part of routine care.
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| CHU Angers Coordinator of this site? Confirm its status | Angers | France | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.