NCT05615883Completed
Effects of Acute and Chronic Exercise on Myeloid-Derived Suppressor Cells in Melanoma Patients
Source: ClinicalTrials.gov · Last updated 15 Oct 2024
Brief summary (registry, in English)
This study is designed to investigate the effects of ketogenic milieu induced by acute exercise as well as the effects of recurrent exercise bouts on functional status and the accumulation in peripheral blood of MDSCs and the consequent balance on antitumor immunity in melanoma patients.
- Status (registry)
- Completed
- Study type
- Interventional
- Enrollment
- 16 (actual)
- First submitted
- 29 Apr 2021
- Start date
- 20 Jan 2020
- Primary completion date
- 30 Nov 2023
- Lead sponsor
- Fondazione IRCCS Istituto Nazionale dei Tumori, Milano
- Diseases
- Melanoma
- NCT number
- NCT05615883
What you commit to
- Study type: Interventional
- Participants enrolled: 16
- From 20 Jan 2020 to the primary completion date, 30 Nov 2023
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- Known infection from HIV virus
- Any physical or mental conditions interfering with the ability to perform exercise or to complete the testing procedures.
Other
- American Society of Anaesthesiologists (ASA) status \> I
- Pregnancy or lactation
- Regular physical exercise (more than 1 exercise workout of moderate to intense exercise activity per week)
Who the study is looking for
- Age from 18 to 65 years at the time of recruitment
- Histologically confirmed diagnosis of primary melanoma
- Patients who are candidate to curative surgery for primary melanoma, skin radicalization or sentinel node biopsy.
- American Society of Anaesthesiologists (ASA) status I
- Willingness and ability to comply with the protocol, the scheduled visits, treatment plans, laboratory tests and other procedures.
- Understanding and signature of the informed consent
- Female patients of childbearing potential must agree to sexual abstinence or to use highly effective method of contraception throughout the study (for CEP patients)
Age in the registry: 18 years to 65 years · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Fondazione IRCCS - Istituto Nazionale dei Tumori Coordinator of this site? Confirm its status | Milan | Italy | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.