NCT05628649Active, not recruiting

Teaching Kitchen Multisite Trial

Teaching Kitchen Multisite Trial (TK-MT)

Source: ClinicalTrials.gov · Last updated 3 Oct 2025

Brief summary (registry, in English)

This TK-MT is an interactive year-long program that teaches culinary skills, nutrition education, mindfulness, and stress reduction, promotes movement, and optimizes behavior change through health coaching strategies. The purpose of this study is to test whether a referral-based teaching kitchen intervention offered for 12 months in adjunct to primary care obesity management is feasible, acceptable, and effective on improving health behaviors and obesity prevention. Specifically, the primary goal of the study is to provide evidence of improved behavior change (ex: increases in cooking at home, fruit and vegetable intake, exercise, sleep, mindful activities), improved lab values (ex: fasting blood glucose, cholesterol, triglycerides, etc.), and resulting change in body weight and waist circumference measures. The hypothesis is that by participating in this novel TK-MT intervention - learning to cook healthy, delicious, inexpensive meals at home; understanding principles of good nutrition (based on the Harvard Healthy Eating Plate); incorporating exercise more effectively into daily living; reducing stress and increasing mindfulness and sleep; and, having access to principles of health coaching - in order to leverage personal motivations - can provide a platform to transform individuals and consequently their health, not only for the duration of this study (16 weeks intensive, 8 months boosters for a total of 12 months) but for their entire lives.

Status (registry): Active, not recruiting
Study type: Interventional
Enrollment: 320 (estimated)
First submitted: 27 Jul 2022
Start date: 1 Sept 2023
Primary completion date: 1 Oct 2025
Lead sponsor: Harvard School of Public Health (HSPH)
Diseases: Obesity
NCT number: NCT05628649

What you commit to

Study type: Interventional
Planned participants: 320
From 1 Sept 2023 to the primary completion date, 1 Oct 2025
5 sites in 1 country
Visits and tests: ask the trial team, the registry does not list them

Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.

Who cannot take part

Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.

Other illness

Taking obesity or diabetes medication (with the exception of metformin) as assessed by the study medical director
Current or past diagnosis of Type 1 or 2 diabetes (excluding past gestational diabetes)
History of severe obesity (BMI\>=40kg/m2)
History of bariatric surgery
Psychiatric hospitalization in the past 12 months
History of significant mental health diagnoses or recent life-threatening illnesses (including unstable cardiovascular disease)
Other medical, psychiatric, or behavioral limitations that in the judgment of the principal investigator or study site PI's may interfere with study participation or the ability to follow the intervention protocols determined by each site's PI

Other

Anaphylactic reaction to food allergens
Relocating out of area in the next 18 months
Current or planned (during study period) participation in a formal longitudinal culinary or weight management program at the time of recruitment (ie-any smart phone apps, a virtual classes, or in person classes or coaching)
Alcohol or substance abuse within the past 12 months
Diet / exercise contraindications to program participation
Prisoners, pregnant women, and women planning to become pregnant over the next 18 months
Unable or unwilling to give informed consent or communicate per protocol with local study staff
Unwilling or unable to participate in all study-related activities

Who the study is looking for

Capacity for consent
Adults living independently
English literate
Aged 25-70 (to capture adults living independently)
Diagnosis of class I or II obesity (BMI 30-39.9 kg/m2)
Abnormality in one of the following metabolic markers (fasting plasma concentrations of glucose, insulin, ALT/AST and lipids including cholesterol, triglycerides, LDL, or HDL)
Available and willing to commit to the 18 month study including: 16 consecutive weekly classes; 8 once a month classes; along with assessments at 0, 4, 12, and 18 months.
- Participants must be able to commit to both in person and virtually participation
Access to two devices, one device with a camera (smartphone, tablet, computer)
Reliable internet connect in their home
- Capable of operating device independently
Minimal operational cooking appliances; specifically cooktop and oven at home.
- Biometric and Anthropometric Markers:
Fasting glucose - minimum: 100 mg/dL; maximum: 125 mg/dL
Hemoglobin A1C - minimum: 5.7% maximum: 6.4%
Triglycerides - minimum: 150 mg/dL; maximum: 500 mg/dL
LDL - minimum: 130 mg/dL; maximum: 190 mg/dL
HDL - minimum: men \< 40 mg/dL; women \< 50 mg/dL
LDL/HDL ratio - minimum: men \> 3.0; women \> 2.5
Blood Pressure - minimum: systolic 130 mmHg and diastolic \<80 mmHg; maximum: uncontrolled HTN per PCP
Waist Circumference - minimum: men \> 94 cm; women \> 80 cm
ALT - minimum: men \> 55 unit/L; women \> 30 unit/L; maximum: 4x limit

Age in the registry: 25 years to 70 years · Sex: All · Does not accept healthy volunteers

Full criteria on ClinicalTrials.gov

Sites (5)

Sites in registry order. Pick your city on the disease page to sort them by distance.

Site	City	Country	Site status
Harvard Coordinating Site Coordinator of this site? Confirm its status	Boston	United States	Unknown status
UTHealth Houston Coordinator of this site? Confirm its status	Houston	United States	Unknown status
University of California, Irvine Coordinator of this site? Confirm its status	Irvine	United States	Unknown status
Dartmouth Health Coordinator of this site? Confirm its status	Lebanon	United States	Unknown status
University of California Los Angelos Coordinator of this site? Confirm its status	Los Angeles	United States	Unknown status

This page is information, not medical advice. Discuss any trial with your doctor.