NCT05629520Completed
A Neurobiological Model of Anhedonia
Inflammatory, Behavioral and Neural Markers of Anhedonia in Major Depressive Disorder
Source: ClinicalTrials.gov · Last updated 16 Oct 2024
Brief summary (registry, in English)
The purpose of this research study is to better understand anhedonia in Major Depressive Disorder by investigating the reward-related neural and inflammatory correlates.
- Status (registry)
- Completed
- Study type
- Observational
- Enrollment
- 60 (actual)
- First submitted
- 31 Oct 2022
- Start date
- Feb 2020
- Primary completion date
- Jul 2024
- Lead sponsor
- Milton S. Hershey Medical Center
- Diseases
- Depression
- NCT number
- NCT05629520
What you commit to
- Study type: Observational
- Participants enrolled: 60
- From Feb 2020 to the primary completion date, Jul 2024
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Comorbid illness such as endocrinological illness (e.g. Cushing's disease) rheumatologic illness (e.g., systemic Lupus erythematosus, current treatment with glucocorticoids), and autoimmune diseases (e.g. psoriasis)
- Daily NSAID or aspirin use and any metallic implant
Other illness
- Comorbid Bipolar Disorder
- Substance use disorder in the last 12 months
- Schizophrenia, and other psychotic disorders
Other
- Pregnancy
- Visual/Hearing Impairments that would keep participant from being able to complete tasks
Who the study is looking for
- Current diagnosis of MDD based on the MINI International Neuropsychiatric Interview (MINI)
- For treatment resistant depression participants: unsuccessful treatment with at least 2 types or doses of antidepressant medication treatment
- Right-handed
- Capacity for informed consent
- Score a 9 or higher on the MADRS
Age in the registry: 18 years to 65 years · Sex: All · Accepts healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Penn State Milton S. Hershey Medical Center Coordinator of this site? Confirm its status | Hershey | United States | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.