NCT05640700Active, not recruiting
Vaginal Microbiome and HPV Pre-malignant and Cervical Dysplasia
Assessing Personalized Vaginal Microbiome Contributions to HPV-driven Pre-malignant and Malignant Cervical Cancer
Source: ClinicalTrials.gov · Last updated 29 Oct 2026
Brief summary (registry, in English)
In this study, the investigators will prospectively collect, analyze and integrate information regarding vaginal microbiome composition and HPV presence in women with cervical pathologies (high-grade CIN and CC) and controls, to construct a large dataset from patients with pre-cancerous cervical lesions and healthy women, to evaluate the personalized contribution of the vaginal microbiome to the CIN-CC sequence.
- Status (registry)
- Active, not recruiting
- Study type
- Observational
- Enrollment
- 99 (actual)
- First submitted
- 28 Nov 2022
- Start date
- 9 Nov 2022
- Primary completion date
- 30 Dec 2027
- Lead sponsor
- Hadassah Medical Organization
- Diseases
- Cervical cancer
- NCT number
- NCT05640700
What you commit to
- Study type: Observational
- Participants enrolled: 99
- From 9 Nov 2022 to the primary completion date, 30 Dec 2027
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Usage of antibiotics in the month prior to clinic visit
- Usage of any vaginal preparation or medication in the week prior to sample collection (anti-fungal, spermicides, lubricant etc.)
Other
- Patient does not approve sample collection
- Menstruation
Who the study is looking for
- Age 25-70
- Attended the clinic for a Pap smear or colposcopy
- Findings of high risk-HPV without cervical dysplasia (based on evaluation done in Kupat Holim)
Age in the registry: 25 years to 70 years · Sex: Female · Accepts healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Hadassah medical Center Coordinator of this site? Confirm its status | Jerusalem | Israel | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.