NCT05643859Recruiting
Impact of Dietary Fiber Supplementation on Colonic Microbiome
Changes in Colonic Microbiome With Fiber Supplementation
Source: ClinicalTrials.gov · Last updated 15 Jan 2026
Brief summary (registry, in English)
This clinical trial tests whether daily fiber supplementation will change the mucosal microbiome of the colon. The microbiome are microorganisms that live in the human gut. They serve a vital role in maintaining health. Certain microbial strains are associated with the growth of colon polyps, which eventually could go on to form colon cancer. Giving dietary fiber supplements may help prevent precancerous polyps from ever developing.
- Status (registry)
- Recruiting
- Study type
- Interventional
- Enrollment
- 120 (estimated)
- First submitted
- 26 Sept 2022
- Start date
- 1 Apr 2023
- Primary completion date
- 31 Dec 2026
- Lead sponsor
- OHSU Knight Cancer Institute
- Diseases
- Colorectal cancer
- NCT number
- NCT05643859
What you commit to
- Study type: Interventional
- Planned participants: 120
- From 1 Apr 2023 to the primary completion date, 31 Dec 2026
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Patients with a prior history of total or partial colon resection
Other illness
- Patients with an active malignancy, Crohn's disease, ulcerative colitis, and immunosuppressed patients
- Patients with hereditary colon cancer syndrome including Lynch syndrome or Familial Adenomatous Polyposis (FAP)
- Colorectal pathology, such cancer or proctitis, after initial study scope
Who the study is looking for
- Age \>= 18 years
- Ability to understand and the willingness to sign a written informed consent document
- Patients who present with a chief complaint of a benign anorectal pathology including hemorrhoids, anal fissures, and anal fistulas without underlying conditions such as colorectal cancer or Crohn's disease or are undergoing a standard of care colonoscopy procedure
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Save your city in your profile to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| OHSU Knight Cancer Institute Coordinator of this site? Confirm its status | Portland | United States | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.