NCT05644327Recruiting
Exercise to Improve Sleep in Parkinson's Disease
The Effects of Different Exercise Modalities on Sleep Quality and Architecture in People With Parkinson's Disease
Source: ClinicalTrials.gov · Last updated 13 Mar 2026
Brief summary (registry, in English)
This study will investigate the impact of three common exercise modalities, cardiovascular, resistance, and multimodal (i.e., a combination of the previous two) training, on sleep quality and architecture in persons with Parkinson's disease (PD). Furthermore, the project will investigate whether the potential positive exercise-induced changes in sleep are associated with improvements in different quality of life (QoL)-related aspects. Participants will perform either cardiovascular training (CT), resistance training (RT), multimodal training (MT), or will be allocated to a control condition (i.e., waiting list - CON) for 12 weeks. Training will be performed three times/week. The assessments will be conducted at baseline, post-intervention, and follow-up (i.e. 8 weeks after the intervention) by assessors blinded to the participants' group allocation.
- Status (registry)
- Recruiting
- Study type
- Interventional
- Enrollment
- 150 (estimated)
- First submitted
- 18 Nov 2022
- Start date
- 1 Sept 2021
- Primary completion date
- 30 Dec 2027
- Lead sponsor
- McGill University
- Diseases
- Parkinson disease
- NCT number
- NCT05644327
What you commit to
- Study type: Interventional
- Planned participants: 150
- From 1 Sept 2021 to the primary completion date, 30 Dec 2027
- 3 sites in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Participating in an exercise or drug trial during the period of the study;
Other illness
- Having atypical parkinsonism, dementia, stroke, or any other neurological condition;
Other
- Presenting severe untreated obstructive sleep apnea (OSA);
- Having a Montreal Cognitive Assessment (MoCA) score \<18
- Having a Beck Depression Inventory score \>31;
- Having absolute contraindications to exercise;
- Having severe osteoporosis;
- Exceeding the physical activity levels recommended for the general population (≥150 minutes/week of moderate-intensity or ≥75 minutes/week of vigorous-intensity cardiovascular activity) and/or strengthening activities ≥2 days/week.
Who the study is looking for
- Persons with mild-moderate idiopathic Parkinson's Disease (Modified Hoehn \& Yahr Scale stages 0.5-3.5);
- On a stable dosage of medication during the previous month;
- Having poor sleep quality defined as a score \> 15 in the PDSS-2 and/or reporting subjective sleep complaints affecting their sleep quality;
Age in the registry: 40 years to - · Sex: All · Does not accept healthy volunteers
Sites (3)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Jewish Rehabilitation Hospital Coordinator of this site? Confirm its status | Laval | Canada | Recruiting |
| Human Brain Control of Locomotion Laboratory Coordinator of this site? Confirm its status | Montreal | Canada | Recruiting |
| Cummings Centre Coordinator of this site? Confirm its status | Montreal | Canada | Not yet recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.