NCT05646888Active, not recruiting
Inflammation, Platelets and Sickle Cell Disease
Source: ClinicalTrials.gov · Last updated 19 Mar 2026
Brief summary (registry, in English)
Sickle cell disease (SCD) is an autosomal recessive genetic disorder linked to a single mutation on beta-globin chains. This leads to red blood cell deformation and chronic hemolysis which can result in vaso-occlusive events, anemia and vasculopathy. Pathophysiology is incompletely understood, and beyond red blood cell's abnormalities this involves hemostasis and innate immunity. The aim of our study is to describe the mechanisms of thrombo-inflammation during the vaso-occlusive crisis (VOC) in adults with sickle cell disease.
- Status (registry)
- Active, not recruiting
- Study type
- Observational
- Enrollment
- 25 (estimated)
- First submitted
- 6 Sept 2022
- Start date
- 15 Jan 2023
- Primary completion date
- 30 Nov 2026
- Lead sponsor
- University Hospital, Toulouse
- Diseases
- Sickle cell disease
- NCT number
- NCT05646888
What you commit to
- Study type: Observational
- Planned participants: 25
- From 15 Jan 2023 to the primary completion date, 30 Nov 2026
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Treatment with aspirin or non steroidal anti inflammatory drug
Age
- Age \< 18 years
Other
- Non consent to participate to the study
- Women in pregnancy or breastfeeding
- Protected patient
- Patient already involved in a study requiring collection of additional biological samples
Who the study is looking for
- Patient with sickle cell disease diagnosis, hospitalized in emergency department and/or internal medicine department
- Patient older than 18 years
- Written consent to participate to the study
- Patient with health insurance
- Patient able to receive information about the study
Age in the registry: 18 years to 99 years · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Save your city in your profile to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| IUCT-Oncopole University Hospital Coordinator of this site? Confirm its status | Toulouse | France | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.