NCT05650905Recruiting
Retinal Neurovascular Coupling in Patients Previously Infected With COVID-19
Source: ClinicalTrials.gov · Last updated 16 May 2025 · Not updated for over 12 months - ask the site whether it is still open
Brief summary (registry, in English)
The Study objective is to measure retinal neurovascular coupling and blood flow parameters in patients previously infected with COVID-19, long COVID-19 and healthy age- and sex- matched control subjects
- Status (registry)
- Recruiting
- Study type
- Observational
- Enrollment
- 90 (estimated)
- First submitted
- 13 Dec 2022
- Start date
- Jul 2021
- Primary completion date
- Dec 2025
- Lead sponsor
- Medical University of Vienna
- Diseases
- Long COVID and ME/CFS
- NCT number
- NCT05650905
What you commit to
- Study type: Observational
- Planned participants: 90
- From Jul 2021 to the primary completion date, Dec 2025
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Symptoms of a clinically relevant illness in the 3 weeks before the first study day
- Blood donation during the previous three weeks
- Blood donation during the previous three weeks
- Blood donation during the previous three weeks
Other illness
- Presence or history of a severe medical condition as judged by the clinical investigator
- History or family history of epilepsy
- History of epilepsia
- Any of the following will exclude a subject with history of COVID-19 infection from the study:
- History or family history of epilepsy
- History of epilepsia
- Any of the following will exclude a subject with long COVID-19 from the study:
- History or family history of epilepsy
- History of epilepsia
- Diabetes mellitus
Other
- Any of the following will exclude a healthy control subject from the study:
- Participation in a clinical trial in the 3 weeks preceding the study
- Presence of any abnormalities preventing reliable measurements in the study eye as judged by the investigator
- Best corrected visual acuity \< 0.8 Snellen
- Pregnancy, planned pregnancy or lactatin
- Presence of any abnormalities preventing reliable measurements in the study eye as judged by the investigator
- Best corrected visual acuity \< 0.8 Snellen
- Ametropy \>6 Dpt
- Pregnancy, planned pregnancy or lactating
- Presence of any abnormalities preventing reliable measurements in the study eye as judged by the investigator
- Best corrected visual acuity \< 0.8 Snellen
- Ametropy \>6 Dpt
- Pregnancy, planned pregnancy or lactating
Who the study is looking for
- Men and women aged over 18 years
- Non-smokers
- Normal findings in the medical history unless the investigator considers an abnormality to be clinically irrelevant
- No previous history of COVID-19 infection
- Negative testing for SARS-CoV-2 seroprevalence using nucleocapsid antibody tests
- Negative PCR test for SARS-CoV-2
- Normal ophthalmic findings, ametropy \< 6 Dpt.
- Men and women aged over 18 years
- Non-smokers
- History of COVID-19 infection (confirmed by a positive PCR test for SARS-CoV2 in the medical history) within the last 6 months
- Positive testing for SARS-CoV-2 seroprevalence using spike protein IgG antibody tests
- Negative PCR test for SARS-CoV-2
- Men and women aged over 18 years
- Non-smokers
- History of COVID-19 infection (confirmed by a positive PCR test for SARS-CoV2 in the medical history)
- Positive testing for SARS-CoV-2 seroprevalence
- Negative PCR test for SARS-CoV-2
- Long Covid according to the latest WHO-Guidelines
Age in the registry: 18 years to - · Sex: All · Accepts healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Medical University of Vienna, Department of Clinical Pharmacology Coordinator of this site? Confirm its status | Vienna | Austria | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.