NCT05653466RecruitingPhase 2
Adaptive Trial Scheduling in Naming Treatment for Aphasia
Integrating Complementary Learning Principles in Aphasia Rehabilitation Via Adaptive Modeling (Sub-study 2: Adaptive Trial Scheduling)
Source: ClinicalTrials.gov · Last updated 11 Dec 2025
Brief summary (registry, in English)
Aphasia is a language disorder caused by stroke and other acquired brain injuries that affects over two million people in the United States and which interferes with life participation and quality of life. Anomia (i.e., word- finding difficulty) is a primary frustration for people with aphasia. Picture-based naming treatments for anomia are widely used in aphasia rehabilitation, but current treatment approaches do not address the long-term retention of naming abilities and do not focus on using these naming abilities in daily life. The current research aims to evaluate novel anomia treatment approaches to improve long-term retention and generalization to everyday life. This study is one of two that are part of a larger grant. This record is for sub-study 2, which will evaluate the benefits of adaptive trial spacing.
- Status (registry)
- Recruiting
- Phase (registry)
- Phase 2
- Study type
- Interventional
- Enrollment
- 32 (estimated)
- First submitted
- 7 Dec 2022
- Start date
- 6 Dec 2023
- Primary completion date
- 31 Jan 2027
- Lead sponsor
- University of Pittsburgh
- Diseases
- Stroke
- NCT number
- NCT05653466
What you commit to
- Study type: Interventional · Phase 2
- Planned participants: 32
- From 6 Dec 2023 to the primary completion date, 31 Jan 2027
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Unmanaged drug / alcohol dependence.
Other illness
- History of other acquired or progressive neurological disease.
- Severe diagnosed mood or behavioral disorders that require specialize mental health interventions.
Other
- Significant language comprehension impairments
Who the study is looking for
- Existing diagnosis of chronic (\>6 months) aphasia subsequent to left hemisphere stroke.
- Impaired performance on 2/8 sections of the Comprehensive Aphasia Test.
- Must have access to a high-speed internet connection and be able to participate in telehealth.
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Language Rehab and Cognition Lab, Department of Communication Sciences and Disorders, School of Health and Rehabilitation Sciences, University of Pittsburgh Coordinator of this site? Confirm its status | Pittsburgh | United States | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.