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NCT05655650Recruiting

Identifying Biomarkers in Alzheimer's Disease

Source: ClinicalTrials.gov · Last updated 18 Sept 2026

Brief summary (registry, in English)

Alzheimer's disease is a severe neurodegenerative disorder of the brain that is characterized by progressive loss of memory and cognitive decline. With the ageing population, AD is a major public health problem affecting nearly 35 million people worldwide with numbers projected to rise to 115.4 million by 2050. AD is the only cause of death among the top ten causes that has no prevention or cure . It is believed that novel treatment of AD needs to start early or even at the prodromal stage in order to be effective. Therefore, there is an urgent need to find accurate methods of early detection before patients with AD develop clinical dementia. This study aims to identify biomarkers for AD in local Chinese population. this study hypothesizes blood-based proteomics, retinal imaging, ASL-MRP and tau PET can improve the accuracy and staging of AD.

Status (registry)
Recruiting
Study type
Observational
Enrollment
300 (estimated)
First submitted
9 Dec 2022
Start date
Sept 2018
Primary completion date
Dec 2030
Lead sponsor
Chinese University of Hong Kong
NCT number
NCT05655650

What you commit to

  • Study type: Observational
  • Planned participants: 300
  • From Sept 2018 to the primary completion date, Dec 2030
  • 1 site in 1 country
  • Visits and tests: ask the trial team, the registry does not list them

Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.

Who cannot take part

Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.

Other illness

  • Clinical diagnosis of non-AD dementia

Other

  • contraindication for MRI or PET

Who the study is looking for

  • Chinese ethnicity
  • \[For dementia group, clinical diagnosis of "probable Alzheimer's disease" according to recommendation from the National Institute on Aging-Alzheimer's Association workgroups (NIA-AA)

Age in the registry: 20 years to - · Sex: All · Accepts healthy volunteers

Full criteria on ClinicalTrials.gov

Sites (1)

Sites in registry order. Pick your city on the disease page to sort them by distance.

SiteCityCountrySite status
Chinese University of Hong Kong
Coordinator of this site? Confirm its status
Hong KongHong Kong SAR ChinaRecruiting

This page is information, not medical advice. Discuss any trial with your doctor.