NCT05656209Not yet recruiting
LA Improves the Prognosis of Patients With ICVD After Surgery
Lactobacillus Acidophilus Improves the Prognosis (Cognitive Function) of Patients With Ischemic Cerebrovascular Disease After Surgery: a Prospective Randomized Controlled Study
Source: ClinicalTrials.gov · Last updated 19 Dec 2022 · Not updated for over 12 months - ask the site whether it is still open
Brief summary (registry, in English)
Ischemic cerebrovascular disease will cause serious harm to the life and safety of patients, and the treatment prognosis is poor. Numerous clinical trials have demonstrated that probiotics can improve cognitive function in people under multimodal. We have previously found that Lactobacillus acidophilus administration could improve cognitive impairment in MCAO and BCAS mice. Therefore, Based on the above research background and the basis of previous studies, we believe that the administration of Lactobacillus acidophilus solid drink (pure Lactobacillus acidophilus strain) can improve the cognitive function of patients with cerebral ischemia through the "brain-gut axis".
- Status (registry)
- Not yet recruiting
- Study type
- Interventional
- Enrollment
- 236 (estimated)
- First submitted
- 19 Aug 2022
- Start date
- 18 Dec 2022
- Primary completion date
- 18 Dec 2022
- Lead sponsor
- Huaqiu Zhang
- NCT number
- NCT05656209
What you commit to
- Study type: Interventional
- Planned participants: 236
- From 18 Dec 2022 to the primary completion date, 18 Dec 2022
- No sites listed in no country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Previous dementia;
- drugs that may or are known to affect cognitive abuse;
Other illness
- hearing or visual impairment;
- Diagnosis of depression, schizophrenia and other mental diseases;
- Patients with Lactobacillus acidophilus allergy.
Other
- alcohol addiction;
- MRI showed severe cerebral infarction;
Who the study is looking for
- 35-60 years old;
- Diagnosed as ischemic cerebrovascular disease, mild to moderate symptoms, can independently complete the neuropsychological test;
- No previous operation history;
- The modified Rankin scale score was 0 or 1;
- Carotid artery ischemic symptoms ≤3 months before treatment;
- Surgical treatment;
Age in the registry: 35 years to 60 years · Sex: All · Does not accept healthy volunteers
This page is information, not medical advice. Discuss any trial with your doctor.