NCT05659173Active, not recruiting
Vitamin D Deficiency With Selected Vitamin D Receptor Gene Polymorphism in Gestational Hypertension
Association of Vitamin D Deficiency With Selected Vitamin D Receptor (VDR) Gene Polymorphism in Gestational Hypertension Among Malaysian Women: A Prospective Genetic Biomarker for Early Intervention Strategy
Source: ClinicalTrials.gov · Last updated 12 Jun 2025
Brief summary (registry, in English)
This study aim to look into the prevalence of Vitamin D deficiency among Malaysian pregnant women and its associated risk factors. Subsequently, vitamin D deficient women with and without gestational hypertension will be investigated for their genetic variation to look for the association of VDR genetic variation and hypertensive disorders in pregnancy.
- Status (registry)
- Active, not recruiting
- Study type
- Observational
- Enrollment
- 180 (estimated)
- First submitted
- 6 Nov 2022
- Start date
- 1 Dec 2022
- Primary completion date
- 30 Jul 2025
- Lead sponsor
- Universiti Putra Malaysia
- Diseases
- High blood pressure
- NCT number
- NCT05659173
What you commit to
- Study type: Observational
- Planned participants: 180
- From 1 Dec 2022 to the primary completion date, 30 Jul 2025
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Women already on vitamin D supplements or any other drugs that can interfere with vitamin D absorption or metabolism at the time of recruitment.
- Women with chronic hypertension diagnosed prior to pregnancy.
Other illness
- Pregnant women with any other chronic disease that is known to affect vitamin D such as, autoimmune disease and any malignancy
Other
- Non-viable pregnancy at the time of recruitment.
Who the study is looking for
- Malay pregnant women with gestational age between 20 weeks till 42 weeks. (The gestational age will be determined from the first day of the last menstrual cycle or measurement of fetal crown rump length)
- Malay pregnant women with viable pregnancy with or without pregnancy induced hypertension or its complications (pre-eclampsia, eclampsia, HELLP syndrome etc).
- Literate in either English or Malay languages.
- Agreement to follow-up till delivery and provision of written informed consent.
Age in the registry: 19 years to 50 years · Sex: Female · Accepts healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Hospital Pengajar UPM Coordinator of this site? Confirm its status | Serdang | Malaysia | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.