NCT05659888Completed
Real Life Lipid Management in Hospitals Not Participating in PENELOPE Trial - Control Population for PENELOPE
PENELOPE-CTRL: Real Life Lipid Management Compared to Protocolized Implementation of the Current Dutch- and ESC-guidelines in Very High-risk CV-patients
Source: ClinicalTrials.gov · Last updated 26 Jul 2024
Brief summary (registry, in English)
Guideline recommended evidence-based clinical care correlates with improved patient outcomes. In real life care, however, adherence to guideline recommendations remains suboptimal. In real life, patients may receive suboptimal treatment and as a result treatment targets are not always met. To support and improve secondary prevention for cardiovascular disease, PENELOPE and PENELOPE-CTRL are designed to support guideline implementation on lipid management and provide valuable feedback to care-givers on real world data.
- Status (registry)
- Completed
- Study type
- Observational
- Enrollment
- 827 (actual)
- First submitted
- 12 Dec 2022
- Start date
- 25 Jul 2022
- Primary completion date
- 31 Jan 2023
- Lead sponsor
- Clinical Operations WCN B.V.
- Diseases
- Coronary artery disease
- NCT number
- NCT05659888
What you commit to
- Study type: Observational
- Participants enrolled: 827
- From 25 Jul 2022 to the primary completion date, 31 Jan 2023
- 13 sites in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Participation in lipid modifying drug trials up to two years after index cardiovascular event
Other
- Pregnant and lactating women
Who the study is looking for
- Age \>18 and ≤70 years
- Alive at hospital discharge after admission for (N)STEMI between 1-1-2019 and 31-08-2020
- Planned for follow-up at a participating PENELOPE CTRL site
- History of T2DM and/or history of ASCVD defined as either one of:
- cerebrovascular disease/ event: transient ischemic attack, cerebral infarction, amaurosis fugax, retinal infarction
- Coronary artery disease/ event: unstable angina pectoris, MI, ACS, coronary revascularization (coronary angioplasty or surgical procedure for coronary bypass)
- Peripheral artery disease (symptomatic and documented obstruction of a distal extremity artery or surgical intervention (percutaneous transluminal angioplasty, bypass or amputation)
Age in the registry: 18 years to 70 years · Sex: All · Does not accept healthy volunteers
Sites (13)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| NoordWest Hospital (NWZ) Coordinator of this site? Confirm its status | Alkmaar | Netherlands | Unknown status |
| Reinier de Graaf Hospital Coordinator of this site? Confirm its status | Delft | Netherlands | Unknown status |
| Deventer Hospital Coordinator of this site? Confirm its status | Deventer | Netherlands | Unknown status |
| Treant Hospital Coordinator of this site? Confirm its status | Emmen | Netherlands | Unknown status |
| Saxenburg Medisch Centrum Coordinator of this site? Confirm its status | Hardenberg | Netherlands | Unknown status |
| Elkerliek Hospital Coordinator of this site? Confirm its status | Helmond | Netherlands | Unknown status |
| Alrijne Hospital Coordinator of this site? Confirm its status | Leiden | Netherlands | Unknown status |
| Isala Hospital Coordinator of this site? Confirm its status | Meppel | Netherlands | Unknown status |
| Canisius Wilhemina Hospital (CWZ) Coordinator of this site? Confirm its status | Nijmegen | Netherlands | Unknown status |
| Haaglanden Hospital Coordinator of this site? Confirm its status | The Hague | Netherlands | Unknown status |
| Haga Hospital Coordinator of this site? Confirm its status | The Hague | Netherlands | Unknown status |
| Diakonessenhuis Utrecht Coordinator of this site? Confirm its status | Utrecht | Netherlands | Unknown status |
| Maxima Medisch Centrum Coordinator of this site? Confirm its status | Veldhoven | Netherlands | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.