NCT05662345Active, not recruiting
ACT-MBC: A Study of Circulating Tumor Cells (CTCs) in Metastatic Breast Cancer (MBC)
ACT-MBC: A Prospective Observational Impact Study of Circulating Tumor Cells (CTCs) in Metastatic Breast Cancer
Source: ClinicalTrials.gov · Last updated 17 Mar 2026
Brief summary (registry, in English)
ACT-MBC prospectively assesses the impact of CTCs on treatment decisions, response assessment and prognosis in MBC patients.
- Status (registry)
- Active, not recruiting
- Study type
- Observational
- Enrollment
- 65 (estimated)
- First submitted
- 14 Dec 2022
- Start date
- 12 Dec 2022
- Primary completion date
- 14 Nov 2025
- Lead sponsor
- Menarini Silicon Biosystems, INC
- Diseases
- Metastatic breast cancer
- NCT number
- NCT05662345
What you commit to
- Study type: Observational
- Planned participants: 65
- From 12 Dec 2022 to the primary completion date, 14 Nov 2025
- 4 sites in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other
- Life expectancy of ≤ 6 months
- Inability to provide blood samples based on the judgment of the treating provider
Who the study is looking for
- Invasive breast cancer with radiographic and/or clinical evidence of advanced metastatic or unresectable disease
- ER+/HER2- patients prior to starting 2nd line therapy or beyond OR ER/Progesterone Receptor (PR)/HER2-negative (Triple Negative) patients prior to starting any line of therapy
- Measurable and/or non-measurable disease is allowed
- Male or female breast cancer is allowed
- Age \> 18 years
- Willingness to provide mandatory blood specimens
- Willing to return to enrolling institution for follow up imaging at least once
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (4)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Mayo Clinic Health System Albert Lea Coordinator of this site? Confirm its status | Albert Lea | United States | Unknown status |
| MCHS Eau Claire Coordinator of this site? Confirm its status | Eau Claire | United States | Unknown status |
| Mayo Clinic Health System Mankato Coordinator of this site? Confirm its status | Mankato | United States | Unknown status |
| Mayo Clinic Coordinator of this site? Confirm its status | Rochester | United States | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.