NCT05664945Active, not recruiting
Rethinking Pulmonary Rehabilitation - a Three-arm Randomised Multicentre Trial
Rethinking Pulmonary Rehabilitation for Patients With COPD: a Three-arm Randomised Multicentre Trial (REPORT-trial)
Source: ClinicalTrials.gov · Last updated 6 Mar 2026
Brief summary (registry, in English)
Pulmonary rehabilitation (PR) is one of the cornerstones of care for people with COPD together with smoking cessation and medical treatment. Despite the compelling evidence for its benefits, pulmonary rehabilitation is delivered to less than 30% of patients with COPD. Access to PR are particularly challenging, and especially for those with the most progressed stages of the disease. Pulmonary Tele-rehabilitation (PTR) and Home-based pulmonary rehabilitation (HPR) are two emerging models using health-care supportive technology that have proven equivalent to the conventional PR programs in patients with COPD who are able and willing to participate in conventional PR. However, much remain unknown regarding patients with COPD unable to access and participate in the conventional out-patient hospital- or community-based PR when offered during routine consultation. No studies have been conducted to specifically intervene towards this group. Response from emerging rehabilitation models for this specific group is a black box with no substantial research. To fulfill its potential of relevance, results from emerging models, such as Pulmonary Telerehabilitation and Home-based pulmonary rehabilitation must be of clinical relevance, and superior to the current 'usual care' (medication and scheduled follow-up control) in patients with COPD unable to access and participate in the conventional out-patient hospital- or community-based PR when offered during routine consultation.
- Status (registry)
- Active, not recruiting
- Study type
- Interventional
- Enrollment
- 180 (estimated)
- First submitted
- 9 Dec 2022
- Start date
- 10 Jan 2023
- Primary completion date
- 7 Oct 2025
- Lead sponsor
- Copenhagen University Hospital, Hvidovre
- Diseases
- COPD
- NCT number
- NCT05664945
What you commit to
- Study type: Interventional
- Planned participants: 180
- From 10 Jan 2023 to the primary completion date, 7 Oct 2025
- 7 sites in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- Cognitive impairment - unable to follow instructions
- Comorbidities where the exercise content is contraindicated (e.g. treatment for diabetic foot ulcer, active cancer treatment, life expectancy \<12-months)
Other
- Participation in conventional PR in the past 24 months
- Impaired hearing or vision - unable to see or hear instruction from a tablet
- Unable to understand and speak Danish
Who the study is looking for
- Indication for pulmonary rehabilitation according to Danish national guidelines
- Unable to access and participate in the conventional out-patient hospital- or community-based PR when offered during routine consultation
- A post-bronchodilator ratio FEV1/FVC \<70% (confirmed physician diagnosis of COPD)
- A post-bronchodilator FEV1 \<80% (degree of airway obstruction) corresponding to GOLD grade 2-4 (moderate to very severe)
- GOLD group B, C, D corresponding to severe respiratory symptoms and/or frequent acute exacerbations
- Able to stand up from a chair (height 44-46cm) and walk 10 meters independently (with or without a walking aid)
- Able to lift both arms to a horizontal level with a minimum of 1 kilogram's dumbbells in each hand
Age in the registry: 40 years to - · Sex: All · Does not accept healthy volunteers
Sites (7)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Copenhagen University Hospital Amager Coordinator of this site? Confirm its status | Copenhagen | Denmark | Unknown status |
| Copenhagen University Hospital Bispebjerg-Frederiksberg Coordinator of this site? Confirm its status | Copenhagen | Denmark | Unknown status |
| Municipality of Copenhagen Coordinator of this site? Confirm its status | Copenhagen | Denmark | Unknown status |
| Copenhagen University Hospital Herlve-Gentofte Coordinator of this site? Confirm its status | Gentofte Municipality | Denmark | Unknown status |
| Copenhagen University Hospital Nordsjaelland Coordinator of this site? Confirm its status | Hillerød | Denmark | Unknown status |
| Copenhagen University Hospital - Hvidovre Coordinator of this site? Confirm its status | Hvidovre | Denmark | Unknown status |
| Bornholms Hospital Coordinator of this site? Confirm its status | Rønne | Denmark | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.