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NCT05665127Active, not recruiting

Point of Care Evaluation of High-sensitivity Cardiac Troponin

Source: ClinicalTrials.gov · Last updated 4 May 2026

Brief summary (registry, in English)

In this observational research project the investigators wish to test new technologies that could allow them to either detect or rule out heart attacks earlier. Currently, when a patient attends the Emergency Department with symptoms that could be due to a heart attack, the patient has a blood test taken from a vein in the arm. This is sent to a laboratory to measure the level of a protein called troponin that is released from the heart when it is damaged. Doctors and nurses use the level of troponin measured in that blood sample, along with a tracing of the heart and an assessment of symptoms, to decide whether the patient is having a heart attack. On average, it takes about 2 hours from the patient arriving at hospital to the doctor or nurse receiving the blood test result so they can make this diagnosis. A device has been designed that can measure troponin by using a drop of blood from a finger prick with the result available in around 10 minutes. This means that if a patient is having a heart attack we can diagnose it earlier and give them treatment. Previous studies have also showed that the majority of patients who attend hospital with chest pain ultimately do not have a heart attack. With this new device the investigators hope to be able to reassure these patients that their symptoms are not due to a heart attack, so the clinical team can concentrate on finding out what else could be causing their chest pain, and ultimately discharge them earlier. The investigators aim to find the best way to use this new device and look at the impact this device has on the length of time from sample to diagnosis and time spent in hospital.

Status (registry)
Active, not recruiting
Study type
Observational
Enrollment
1000 (estimated)
First submitted
6 Dec 2022
Start date
16 Nov 2022
Primary completion date
28 Feb 2025
Lead sponsor
University of Edinburgh
NCT number
NCT05665127

What you commit to

  • Study type: Observational
  • Planned participants: 1000
  • From 16 Nov 2022 to the primary completion date, 28 Feb 2025
  • 1 site in 1 country
  • Visits and tests: ask the trial team, the registry does not list them

Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.

Who cannot take part

Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.

Prior treatment

  • Previous enrolment in this study

Other illness

  • Patients presenting with an out-of-hospital cardiac arrest

Other

  • Patients with ST-segment elevation on the electrocardiogram
  • Patients unable or unwilling to give informed consent
  • Patients unable or unwilling to comply with study protocol

Who the study is looking for

  • Presenting to hospital with symptoms of suspected acute coronary syndrome
  • Age 18 years and over

Age in the registry: 18 years to - · Sex: All

Full criteria on ClinicalTrials.gov

Sites (1)

Sites in registry order. Save your city in your profile to sort them by distance.

SiteCityCountrySite status
NHS Lothian
Coordinator of this site? Confirm its status
EdinburghUnited KingdomUnknown status

This page is information, not medical advice. Discuss any trial with your doctor.