NCT05670379CompletedPhase 1
Assessment of Safety, Tolerability and Drug Levels of Exenatide Implant
A Randomized, Parallel-Group Study to Assess the Safety, Tolerability, and Pharmacokinetics of Exenatide Implant
Source: ClinicalTrials.gov · Last updated 23 Sept 2025
Brief summary (registry, in English)
The purpose of this study is to evaluate the safety, tolerability and drug levels of an exenatide implant administered subcutaneously.
- Status (registry)
- Completed
- Phase (registry)
- Phase 1
- Study type
- Interventional
- Enrollment
- 24 (actual)
- First submitted
- 13 Dec 2022
- Start date
- 20 Dec 2024
- Primary completion date
- 21 Aug 2025
- Lead sponsor
- Vivani Medical, Inc
- Diseases
- Obesity
- NCT number
- NCT05670379
What you commit to
- Study type: Interventional · Phase 1
- Participants enrolled: 24
- From 20 Dec 2024 to the primary completion date, 21 Aug 2025
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- Has a clinically significant medical condition that could potentially affect study participation and/or personal well-being
- History of Type 1 or Type 2 Diabetes
- Has medullary thyroid carcinoma (MTC) or multiple endocrine neoplasia (MEN II) or a family history of MTC or MEN II
Lab values
- History of, or currently has, acute or chronic pancreatitis or has triglyceride concentrations ≥500 mg/dL
Other
- Current or past exposure to exenatide
Who the study is looking for
- BMI 27 to 40 kg/m\^2
- Estimated glomerular filtration rate (eGFR) \>/= 90 mL/min/1.73 m\^2
- HbA1c \< 6.0% and FPG \< 6.7 mol/L
Age in the registry: 18 years to 55 years · Sex: All · Accepts healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| CMAX Coordinator of this site? Confirm its status | Adelaide | Australia | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.