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NCT05673915Recruiting

Study of Transcranial Direct Current Stimulation to Treat Epilepsy

Pilot Study of Transcranial Direct Current Stimulation (tDCS) to Treat Epilepsy

Source: ClinicalTrials.gov · Last updated 28 Jan 2026

Brief summary (registry, in English)

The purpose of this research is to see to what extent electrical stimulation applied to the scalp (transcranial direct current stimulation or tDCS) can reduce the number and intensity of epileptic seizures.

Status (registry)
Recruiting
Study type
Interventional
Enrollment
30 (estimated)
First submitted
30 Dec 2022
Start date
12 Apr 2023
Primary completion date
Dec 2026
Lead sponsor
Mayo Clinic
Diseases
Epilepsy
NCT number
NCT05673915

What you commit to

  • Study type: Interventional
  • Planned participants: 30
  • From 12 Apr 2023 to the primary completion date, Dec 2026
  • 1 site in 1 country
  • Visits and tests: ask the trial team, the registry does not list them

Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.

Who cannot take part

Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.

Other illness

  • A disease likely to progress over course of the study.
  • Psychogenic non-epileptic seizures.
  • Suicide attempt or psychiatric hospitalization past 2 years.
  • A skin condition interfering with scalp electrodes or allergy to silver.

Lab values

  • Women will verify not pregnant, and if applicable, have a serum pregnancy test.

Other

  • Implanted devices (e.g. pacemakers)-except VNS, which is allowed.

Who the study is looking for

  • Clinical diagnosis of generalized onset or focal epilepsy or sleep-related epileptic encephalopathy.
  • Estimated to have at least 2 countable seizures per month or spike-wave index ≥50%.
  • Has not had control with at least 2 anti-seizure medicines.
  • Able to maintain a constant medication for duration of the study (rescue meds allowed).
  • Subject or legally authorized representative is able to understand consent and keep a seizure diary in English.

Age in the registry: 6 years to - · Sex: All · Does not accept healthy volunteers

Full criteria on ClinicalTrials.gov

Sites (1)

Sites in registry order. Pick your city on the disease page to sort them by distance.

SiteCityCountrySite status
Mayo Clinic Minnesota
Coordinator of this site? Confirm its status
RochesterUnited StatesRecruiting

This page is information, not medical advice. Discuss any trial with your doctor.