NCT05676047Completed
Cognitive Rehabilitation for Long COVID
Symptom-Targeted Rehabilitation for Cognitive Complaints in Long COVID (STAR-C3)
Source: ClinicalTrials.gov · Last updated 23 Jan 2025
Brief summary (registry, in English)
The investigators are comparing two different methods for helping adults with Long Coronavirus (COVID) also known as Post-Coronavirus Syndrome or Post-Coronavirus Condition manage everyday cognitive challenges. Cognitive rehabilitation is a type of therapy that helps people who have challenges with everyday thinking because of a brain injury. One of the investigators on this project along with colleagues in the United States (US) have developed a streamlined version of cognitive rehabilitation therapy for mild traumatic brain injury (mTBI) that can be completed in person or virtually and takes place over a 3-week period. The therapy was originally designed for adults with mTBI. The investigators want to know if it can also be used to treat people with cognitive complaints from Long COVID. The investigators will provide education materials only to one group and individual cognitive rehabilitation delivered by a trained Speech Language Pathologist (SLP) or Occupational Therapist (OT) to the other group. The investigators want to find out whether the individual therapy is as feasible and accessible than the usual educational material. What the investigators learn in this study may help treat day-to-day thinking challenges in Long COVID.
- Status (registry)
- Completed
- Study type
- Interventional
- Enrollment
- 100 (actual)
- First submitted
- 4 Jan 2023
- Start date
- 1 May 2023
- Primary completion date
- 21 Jan 2025
- Lead sponsor
- McMaster University
- Diseases
- Long COVID and ME/CFS
- NCT number
- NCT05676047
What you commit to
- Study type: Interventional
- Participants enrolled: 100
- From 1 May 2023 to the primary completion date, 21 Jan 2025
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- A score of less than 20 on the Montreal Cognitive Assessment (MoCA), which indicates a risk for dementia.
Other
- Cannot identify at least 3 problems on the Common Cognitive Complaints after Concussion Questionnaire (C4), as there would be insufficient areas for intervention.
Who the study is looking for
- Is a community-dwelling adults
- Is age 18 years or older
- Self-identifies as a fluent English speaker
- Have a history of COVID symptoms as listed on the Government of Canada COVID information website, a positive antigen or polymerase chain reaction (PCR) test, or both
- Have cognitive symptoms that have persisted a minimum of 12 weeks after contracting COVID
- Have cognitive symptoms attributable to COVID and not to other intervening diagnoses associated with cognitive dysfunction (e.g., psychosis, concussion), or medications with negative effects on cognitive function
- Have no previous history of a diagnosis of a neurological disorder affecting thinking (e.g., dementia)
- Are able to participate in 3 one-hour sessions per week for 4-6 weeks
- Are not in active behavioural treatment for a substance-use or mental-health disorder, or in cognitive rehabilitation provided by a registered health professional (e.g., speech-language pathologist or occupational therapist)
- Can access an electronic device with internet access and capability for Zoom videoconferencing
Age in the registry: 18 years to 100 years · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Save your city in your profile to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| McMaster University Coordinator of this site? Confirm its status | Hamilton | Canada | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.