NCT05678218Completed
Preoperative Evaluation of Lymph Nodes of Cholangiocarcinoma
Preoperative Evaluation of Lymph Nodes of Cholangiocarcinoma - a Registration Study
Source: ClinicalTrials.gov · Last updated 8 Aug 2025
Brief summary (registry, in English)
The goal of this observational cohort study is to assess the yield of preoperative endoscopic ultrasound focussed on lymph nodes in patients with presumed resectable perihilar (pCCA), intrahepatic (iCCA) or mid-common bile duct (CBD) cholangiocarcinoma. The main questions it aims to answer is: 1. The number of patients precluded from surgical work-up due to positive regional or extraregional lymph nodes identified by endoscopic ultrasound guided tissue acquisition 2. Characteristics during endoscopic ultrasound of lymph nodes associated with malignancy
- Status (registry)
- Completed
- Study type
- Observational
- Enrollment
- 245 (actual)
- First submitted
- 23 Dec 2022
- Start date
- 5 Sept 2022
- Primary completion date
- 1 Jul 2025
- Lead sponsor
- Erasmus Medical Center
- Diseases
- Liver and biliary tract cancer
- NCT number
- NCT05678218
What you commit to
- Study type: Observational
- Participants enrolled: 245
- From 5 Sept 2022 to the primary completion date, 1 Jul 2025
- 7 sites in 2 countries
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- Patients with a history of treated CCA
- Patients with a history of treated liver malignancy
Lab values
- Patients with a contra-indication for EUS-tissue acquisition (f.e. uncorrectable coagulopathy or platelet disorder), in line with current clinical practice
Other
- Patients with CCA for which a pancreatoduodenectomy is indicated, based on cross-sectional imaging
Who the study is looking for
- Presumed resectable pCCA OR
- Presumed resectable iCCA OR
- Presumed resectable mid-common bile duct CCA OR
- Presumed unresectable pCCA worked-up for Liver Transplantation AND
- Written informed consent must be given according to International Council on Harmonisation/Good Clinical Practice guidelines, and national/local regulations AND
- Age \> 18 years.
Age in the registry: 18 years to 110 years · Sex: All · Does not accept healthy volunteers
Sites (7)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| University Hospital of Ghent Coordinator of this site? Confirm its status | Ghent | Belgium | Unknown status |
| Amsterdam University Medical Center Coordinator of this site? Confirm its status | Amsterdam | Netherlands | Unknown status |
| University Medical Center Groningen Coordinator of this site? Confirm its status | Groningen | Netherlands | Unknown status |
| Leiden University Medical Center Coordinator of this site? Confirm its status | Leiden | Netherlands | Unknown status |
| Maastricht UMC Coordinator of this site? Confirm its status | Maastricht | Netherlands | Unknown status |
| Erasmus University Medical Center Coordinator of this site? Confirm its status | Rotterdam | Netherlands | Unknown status |
| University Medical Center Utrecht Coordinator of this site? Confirm its status | Utrecht | Netherlands | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.