NCT05679297Completed
Structural and Functional Grey and White Matter Changes in Patients With Pain Disorders
Source: ClinicalTrials.gov · Last updated 17 Jan 2025
Brief summary (registry, in English)
The goal of this observational study is to examine the association between exact lesion location and presence of thalamic CPSP (Central post-stroke pain) in a larger number of patients after thalamic stroke.
- Status (registry)
- Completed
- Study type
- Observational
- Enrollment
- 82 (actual)
- First submitted
- 21 Dec 2022
- Start date
- 4 May 2015
- Primary completion date
- 27 Dec 2024
- Lead sponsor
- University Hospital, Basel, Switzerland
- NCT number
- NCT05679297
What you commit to
- Study type: Observational
- Participants enrolled: 82
- From 4 May 2015 to the primary completion date, 27 Dec 2024
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- History of severe neurological, internistic or psychiatric disease
Other
- MRI related exclusion criteria:
- paramagnetic and/or superparamagnetic foreign objects in the body (especially when located close to the brain)
- Pacemaker
- Claustrophobia
- Pregnancy
Who the study is looking for
- Patients with thalamic central post-stroke pain (CPSP) :
- Patients fulfilling all of the following inclusion criteria are eligible for the study:
- Informed Consent as documented by signature (Appendix Informed Consent Form)
- History of thalamic stroke (infarction or bleed)
- Diagnosis of definite central-post stroke pain (according to the criteria proposed by Klit et al, 2009)
- No other chronic pain condition
- Age: ≥18 years old
- Patients with thalamic stroke without CPSP:
- Patients fulfilling all of the following inclusion criteria are eligible for the study:
- Informed Consent as documented by signature (Appendix Informed Consent Form)
- History of thalamic stroke (infarction or bleed), at least 2 years ago
- No chronic pain condition (neither CPSP or other pain condition)
- Age ≥18 years old
- Patients with migraine (other pain condition):
- Patients fulfilling all of the following inclusion criteria are eligible for the study:
- Informed Consent as documented by signature (Appendix Informed Consent Form)
- History of highly frequent (≥8 monthly migraine days) or chronic migraine (≥15 monthly migraine days).
- No history of stroke
- Age ≥18 years old
- Healthy controls:
- Participants fulfilling all of the following inclusion criteria are eligible for the study:
- Informed Consent as documented by signature (Appendix Informed Consent Form)
- No history of stroke
- No chronic pain condition
- Age: ≥18 years old
Age in the registry: 18 years to - · Sex: All · Accepts healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| University Hospital Basel, Department of Neurology Coordinator of this site? Confirm its status | Basel | Switzerland | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.