NCT05686330Completed
Detection and Quantification of Atrial Fibrillation in High-risk Patients Using a Smartwatch Wearable (Apple Watch)
Enhanced Detection and Quickened Diagnosis of Atrial Fibrillation Using the Apple Watch: A Randomised Controlled Trial (EQUAL Study)
Source: ClinicalTrials.gov · Last updated 16 Sept 2025
Brief summary (registry, in English)
This is a randomized controlled trial evaluating atrial fibrillation (AF) detection through smartwatch-based screening in high-risk patients using an Apple Watch with integrated PPG and ECG functions.
- Status (registry)
- Completed
- Study type
- Interventional
- Enrollment
- 436 (actual)
- First submitted
- 16 Dec 2022
- Start date
- 16 Nov 2022
- Primary completion date
- 17 Jul 2025
- Lead sponsor
- Amsterdam University Medical Centers (UMC), Location Academic Medical Center (AMC)
- Diseases
- Atrial fibrillation
- NCT number
- NCT05686330
What you commit to
- Study type: Interventional
- Participants enrolled: 436
- From 16 Nov 2022 to the primary completion date, 17 Jul 2025
- 2 sites in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Currently on anticoagulation therapy
Other illness
- Cardiac implanted electronic device (pacemaker, ICD)
- Smartwatch cannot be worn due to comprehensible reasons (allergic reactions, wounds, amputations, other)
- Significant mental or cognitive impairment
Other
- Diagnosis of atrial fibrillation or atrial flutter
Who the study is looking for
- Age ≥ 65 years
- Chadsvasc score ≥2 for men and ≥ for women at the time of eligibility screening
- Written informed consent as documented by signature from the participant
- Possession of iPhone (6S or later)
Age in the registry: 65 years to - · Sex: All · Does not accept healthy volunteers
Sites (2)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Cardiology Center of the Netherlands Coordinator of this site? Confirm its status | Amsterdam | Netherlands | Unknown status |
| Spaarne Gasthuis Coordinator of this site? Confirm its status | Haarlem | Netherlands | Unknown status |
Related publications
- Enhanced Detection and Prompt Diagnosis of Atrial Fibrillation Using Apple Watch: A Randomized Controlled Trial.J Am Coll Cardiol · 2026 · PMID 41569211
This page is information, not medical advice. Discuss any trial with your doctor.