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NCT05688683Recruiting

Brain Representation of Acquisition in Humans of Motor-Sensory Skills

Source: ClinicalTrials.gov · Last updated 5 Jan 2026

Brief summary (registry, in English)

Interactions between the perceptual and motor systems are fundamental to the performance of complex motor tasks and are at the heart of the fine motor control required for the production of complex sounds such as speech production or playing a musical instrument. In such situations, the brain must learn to generate relevant motor commands to a sound-producing system with fixed physical characteristics, such as the vocal tract or a musical instrument. No study has yet been able to directly test the dynamic aspect of this sensorimotor learning in an acoustic production task with fine motor control. The Adolphe de Rothschild Foundation Hospital takes care of patients requiring awake surgery. During these procedures, a direct cortical recording, called electro-corticography, is performed in order to better delineate the tumor or epileptogenic resection area. Reference recordings are made in healthy areas at a distance from the lesion site making it possible to record normal brain activity. In this case, we would propose to the patient to use a tool similar to the theremin (a musical instrument the size of a golf ball whose displacement in space modulates the frequency and the harmonics of a sound). The patient should therefore learn in order to create relevant motor patterns.

Status (registry)
Recruiting
Study type
Observational
Enrollment
50 (estimated)
First submitted
9 Jan 2023
Start date
4 Jan 2023
Primary completion date
Mar 2028
Lead sponsor
Fondation Ophtalmologique Adolphe de Rothschild
Diseases
Epilepsy
NCT number
NCT05688683

What you commit to

  • Study type: Observational
  • Planned participants: 50
  • From 4 Jan 2023 to the primary completion date, Mar 2028
  • 1 site in 1 country
  • Visits and tests: ask the trial team, the registry does not list them

Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.

Who cannot take part

Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.

Other illness

  • Patient with a disorder or impairment that does not allow him/her to perform the experimental task according to the investigator's judgment

Other

  • Patient with complete deafness

Who the study is looking for

  • Benefiting from an intracranial brain recording during a programmed surgery in awake condition.

Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers

Full criteria on ClinicalTrials.gov

Sites (1)

Sites in registry order. Pick your city on the disease page to sort them by distance.

SiteCityCountrySite status
Fondation Adolphe de Rothschild
Coordinator of this site? Confirm its status
ParisFranceRecruiting

This page is information, not medical advice. Discuss any trial with your doctor.