NCT05691192CompletedPhase 2
Cognitive Reserve-building Activities in Multiple Sclerosis
Cognitive Reserve-building Activities in Multiple Sclerosis: a Randomized Controlled Trial of the Effect of Cognitive Leisure Activities on Objective and Subjective Measures of Cognition
Source: ClinicalTrials.gov · Last updated 18 Feb 2025
Brief summary (registry, in English)
The study is a crossover randomized controlled trial investigating the effect of increasing engagement in cognitive leisure activities for individuals with multiple sclerosis.
- Status (registry)
- Completed
- Phase (registry)
- Phase 2
- Study type
- Interventional
- Enrollment
- 60 (actual)
- First submitted
- 6 Jan 2023
- Start date
- 1 Dec 2022
- Primary completion date
- 27 Nov 2024
- Lead sponsor
- Copenhagen University Hospital, Rigshospitalet
- Diseases
- Multiple sclerosis
- NCT number
- NCT05691192
What you commit to
- Study type: Interventional · Phase 2
- Participants enrolled: 60
- From 1 Dec 2022 to the primary completion date, 27 Nov 2024
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Planned start-up or discontinuation of one or more of the above-mentioned medications
- Structural brain changes following previous head trauma or neurological conditions other than which lead to structural changes or affect cognitive abilities
- Relapse 3 months prior to inclusion
Other illness
- Epilepsy
- Significant psychiatric co-morbidity
- Significant somatic co-morbidity including, but not limited to, severe cardiovascular disease as well as liver, kidney, and endocrine diseases
Who the study is looking for
- RRMS, SPMS or PPMS
- Age 18-65
- EDSS score ≤ 6.5
- SDMT (or PASAT) score below -1 SD
- No depression based on the MDI
- Able to use computer or smartphone and has internet access
- If in treatment with one or more of the following medications, the dosage must be stable:
- Cannabinoids
- Anticholinergic medications
- Sedatives e.g., benzodiazepines
- Opioids
- Antispasmodics
- Beta-blockers
- Antidepressant medication
- Fampridine
Age in the registry: 18 years to 65 years · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Danish Multiple Sclerosis Center, Copenhagen University Hospital, Rigshospitalet-Glostrup Coordinator of this site? Confirm its status | Glostrup Municipality | Denmark | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.