NCT05694065Active, not recruiting
Functional ComprEhensive AssessmenT by IVUS Reconstruction in Patients With Suspected IschEmic Heart Disease (FEATURE)
Functional ComprEhensive AssessmenT by Intravascular UltrasoUnd Reconstruction in Patients With Suspected IschEmic Coronary Artery Disease (FEATURE)
Source: ClinicalTrials.gov · Last updated 24 Jul 2026
Brief summary (registry, in English)
Investigating the diagnostic accuracy of online Ultrasonic Flow Ratio (UFR) assessment to identify hemodynamically significant coronary stenosis in patients with suspected ischemic heart disease using angiography-derived fractional flow reserve (FFR) as a reference standard.
- Status (registry)
- Active, not recruiting
- Study type
- Observational
- Enrollment
- 112 (actual)
- First submitted
- 12 Jan 2023
- Start date
- 17 Feb 2023
- Primary completion date
- 22 Nov 2024
- Lead sponsor
- Ruijin Hospital
- Diseases
- Coronary artery disease
- NCT number
- NCT05694065
What you commit to
- Study type: Observational
- Participants enrolled: 112
- From 17 Feb 2023 to the primary completion date, 22 Nov 2024
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Patients with previous coronary artery bypass grafting (CABG)
Other illness
- Myocardial infarction within 72h of coronary angiography
- Allergy to the contrast agent or adenosine
- Target vessel with severe myocardial bridge
- Target vessel with severe thrombosis
- Heart failure
Lab values
- A serum creatinine level \>150 umol/l, or a glomerular filtration rate \< 45 ml/kg/1.73 m\^2
Other
- Left main coronary artery stenosis ≥ 50%
- Target vessel with in-stent restenosis
- Target vessel with severe tortuosity or angulation
- 100% occlusion of target vessel
- Target vessel spasm or injury
- Intravascular ultrasound (IVUS) pullback fails to cover the complete target lesion
- Presence of false lumen at target vessel based on IVUS
- Ineligible for diagnostic intervention (IVUS or FFR examination)
Who the study is looking for
- Subject must be ≥ 18 years
- Patients suspected with ischemic heart disease
- ≥ 1 diseased vessel with angiographic percent diameter stenosis between 40% and 80% in a vessel ≥ 2.5mm by visual estimation
- Target vessels are limited to major epicardial coronary arteries (left anterior descending artery \[LAD\], left circumflex artery \[LCX\], right coronary artery \[RCA\])
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Ruijin Hospital, Shanghai Jiao Tong University School of Medicine Coordinator of this site? Confirm its status | Shanghai | China | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.