NCT05694637Enrolling by invitationPhase 4
Botswana Smoking and Abstinence Reinforcement Trial
Source: ClinicalTrials.gov · Last updated 9 Jan 2026
Brief summary (registry, in English)
Many people living with HIV in southern Africa, specifically Botswana use tobacco products. Using tobacco makes some of the effects of HIV worse and even causes excess deaths. The investigators plan to use an intervention called Screening, Brief Intervention and Referral to Treatment (SBIRT) to help people to quit smoking and also a drug called varenicline. Apart from helping people to stop smoking, the investigators will also test to see how task shifting can be used to help people stop smoking in a sustainable way. Finally, the investigators will estimate the cost of the intervention.
- Status (registry)
- Enrolling by invitation
- Phase (registry)
- Phase 4
- Study type
- Interventional
- Enrollment
- 750 (estimated)
- First submitted
- 7 Dec 2022
- Start date
- 25 Jul 2023
- Primary completion date
- 1 Feb 2027
- Lead sponsor
- University of Maryland, Baltimore
- Diseases
- HIV
- NCT number
- NCT05694637
What you commit to
- Study type: Interventional · Phase 4
- Planned participants: 750
- From 25 Jul 2023 to the primary completion date, 1 Feb 2027
- 15 sites in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Age
- Less than 18 years of age
Other
- Pregnant
- Unable or cognitively impaired to provide consent
Who the study is looking for
- HIV infected
- Self reported current daily smoker
- Age 18 and older
- Engaged in HIV care as defined by being on ART for at least 6 months
- Willing/able to provide informed consent in English or Setswana
Age in the registry: 18 years to - · Sex: All · Accepts healthy volunteers
Sites (15)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Nyangabgwe Referral Hospital Coordinator of this site? Confirm its status | Francistown | Botswana | Unknown status |
| Masego Clinic Coordinator of this site? Confirm its status | Francistown | Botswana | Unknown status |
| Itekeng Clinic Coordinator of this site? Confirm its status | Francistown | Botswana | Unknown status |
| Goodhope Primary Hospital Coordinator of this site? Confirm its status | Good Hope | Botswana | Unknown status |
| Kanye Adventist Hospital Coordinator of this site? Confirm its status | Kanye | Botswana | Unknown status |
| Mahalapye District Hospital Coordinator of this site? Confirm its status | Mahalapye | Botswana | Unknown status |
| Airstrip Clinic Coordinator of this site? Confirm its status | Mahalapye | Botswana | Unknown status |
| Morwa Clinic Coordinator of this site? Confirm its status | Mochudi | Botswana | Unknown status |
| Kediretswe Clinic Coordinator of this site? Confirm its status | Palapye | Botswana | Unknown status |
| Palpye Primary Hospital Coordinator of this site? Confirm its status | Palapye | Botswana | Unknown status |
| Sefhare Primary Hospital Coordinator of this site? Confirm its status | Sefhare | Botswana | Unknown status |
| Serowe Clinic Coordinator of this site? Confirm its status | Serowe | Botswana | Unknown status |
| Sekgoma District Hospital Coordinator of this site? Confirm its status | Serowe | Botswana | Unknown status |
| Thamaga Primary Hospital Coordinator of this site? Confirm its status | Thamaga | Botswana | Unknown status |
| Tutume Primary Hospital Coordinator of this site? Confirm its status | Tutume | Botswana | Unknown status |
Related publications
- A qualitative investigation of tobacco use and cessation experiences among people living with HIV in Botswana.Discov Public Health · 2026 · PMID 42763466
This page is information, not medical advice. Discuss any trial with your doctor.