NCT05701280Active, not recruiting
Pilot/Pivotal Study of DBS+Rehab After Stroke
Rehab With Electrical Stimulation Therapy to Optimize Rehabilitation Effect (RESTORE): A Pivotal Study
Source: ClinicalTrials.gov · Last updated 5 Oct 2026
Brief summary (registry, in English)
The RESTORE Stroke Study will evaluate the safety and effectiveness of DBS+Rehab for treating arm weakness and reduced function after a stroke.
- Status (registry)
- Active, not recruiting
- Study type
- Interventional
- Enrollment
- 202 (estimated)
- First submitted
- 9 Jan 2023
- Start date
- 3 Feb 2023
- Primary completion date
- 31 Jan 2027
- Lead sponsor
- Enspire DBS Therapy, Inc.
- Diseases
- Stroke
- NCT number
- NCT05701280
What you commit to
- Study type: Interventional
- Planned participants: 202
- From 3 Feb 2023 to the primary completion date, 31 Jan 2027
- 9 sites in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Previous or subsequent cerebrovascular events resulting in residual upper extremity impairment
Other
- Brain lesions with significant involvement of the brainstem, cerebellum, or thalamus
Who the study is looking for
- Ischemic stroke, with an initial incident occurring between 12 months to 6 years before implant, resulting in residual upper extremity hemiparesis.
Age in the registry: 21 years to - · Sex: All · Does not accept healthy volunteers
Sites (9)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Johns Hopkins School of Medicine Coordinator of this site? Confirm its status | Baltimore | United States | Unknown status |
| Massachusetts General Hospital Coordinator of this site? Confirm its status | Boston | United States | Unknown status |
| Medical University of South Carolina (MUSC) Coordinator of this site? Confirm its status | Charleston | United States | Unknown status |
| Cleveland Clinic Coordinator of this site? Confirm its status | Cleveland | United States | Unknown status |
| NYU Langone Health Coordinator of this site? Confirm its status | New York | United States | Unknown status |
| Thomas Jefferson University Coordinator of this site? Confirm its status | Philadelphia | United States | Unknown status |
| Barrow Neurological Institute (BNI) Coordinator of this site? Confirm its status | Phoenix | United States | Unknown status |
| Rhode Island Hospital Coordinator of this site? Confirm its status | Providence | United States | Unknown status |
| Mayo Clinic Coordinator of this site? Confirm its status | Rochester | United States | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.