NCT05706493Completed
Association Between Periodontitis and the Level of Anti-citrullinated Protein Antibodies in Rheumatoid Arthritis
Association Between Severity of Periodontitis and the Level of Anti-citrullinated Protein Antibodies (ACPAs) in Rheumatoid Arthritis Patients
Source: ClinicalTrials.gov · Last updated 7 Jul 2026
Brief summary (registry, in English)
the relationship between rheumatoid arthritis and periodontal disease is crucial and has been explained via a complex interplay of genetic, environmental, and hormonal factors that influence the host immune tolerance leading to both disease characteristics. The aim of this study is to clinically investigate the correlation between the levels of anti-citrullinated protein antibodies (ACPAs) in gingival crevicular fluid and the severity of periodontal disease and rheumatoid arthritis in rheumatoid arthritis (RA) patients
- Status (registry)
- Completed
- Study type
- Observational
- Enrollment
- 62 (actual)
- First submitted
- 23 Jan 2023
- Start date
- 1 Mar 2024
- Primary completion date
- 1 Jan 2025
- Lead sponsor
- Misr International University
- Diseases
- Rheumatoid arthritis
- NCT number
- NCT05706493
What you commit to
- Study type: Observational
- Participants enrolled: 62
- From 1 Mar 2024 to the primary completion date, 1 Jan 2025
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Antibiotic therapy during last 3 months
Other illness
- Diabetes Mellitus
- Other autoimmune diseases
Other
- Smoking
- Pregnant females
- Patients who had undergone periodontal treatment within last 3 months
Who the study is looking for
- Rheumatoid patients fulfilling the ACR criteria for the classification of RA
- 18 years
- Both genders
- Presence of at least 8 teeth
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Faculty of oral and dental medicine, Misr international university Coordinator of this site? Confirm its status | Cairo | Egypt | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.