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NCT05714696Completed

Weight Discrimination and Poor Cardiovascular Health

Mechanisms Explaining the Link Between Weight Discrimination and Poor Cardiovascular Health

Source: ClinicalTrials.gov · Last updated 15 May 2025

Brief summary (registry, in English)

People with obesity regularly experience discrimination on the basis of their body weight and such experiences are associated with increased risk for poor cardiovascular health. The goal of this clinical trial is to identify cognitive, affective, behavioral, and physiological factors that explain the relationship between weight discrimination and poor health outcomes. A diverse sample of adults with obesity will be randomly assigned to a social interaction encounter that simulates a typical weight discrimination experience (experimental manipulation) vs. a control manipulation that does not involve discrimination. The investigators will examine the immediate effects of the experimental manipulation on cognitive (e.g., self-regulation), affective (e.g., negative emotion), behavioral (e.g., comfort eating), and physiological (e.g., cortisol secretion) outcomes. Two additional aims of the study are to identify psychological traits that moderate responses to weight discrimination and to assess whether the negative health effects of weight discrimination differ by age, sex/gender, race, or ethnicity.

Status (registry)
Completed
Study type
Interventional
Enrollment
333 (actual)
First submitted
6 Jan 2023
Start date
5 Feb 2023
Primary completion date
26 Apr 2024
Lead sponsor
Florida State University
Diseases
Obesity
NCT number
NCT05714696

What you commit to

  • Study type: Interventional
  • Participants enrolled: 333
  • From 5 Feb 2023 to the primary completion date, 26 Apr 2024
  • 1 site in 1 country
  • Visits and tests: ask the trial team, the registry does not list them

Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.

Who cannot take part

Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.

Other illness

  • (2) diagnosed with a current major psychiatric disorder (e.g., major depressive disorder, eating disorder)
  • (4) diagnosed with Cushing syndrome or taking steroid-based medications
  • (5) having allergies to ingredients in the foods being offered during the taste test (e.g., gluten, peanuts).

Other

  • (1) having participated in any of our pilot studies on weight stigma
  • (3) pregnant or nursing

Who the study is looking for

  • (1) body mass index (BMI) greater than or equal to 30 (units: weight in kilograms divided by height in meters squared; BMI criteria for obesity)
  • (2) 18 years of age or older
  • (3) able to read and understand English
  • (4) have Internet access (to complete the baseline survey)
  • (5) able to come to FSU's campus to take part in a lab-based study

Age in the registry: 18 years to - · Sex: All · Accepts healthy volunteers

Full criteria on ClinicalTrials.gov

Sites (1)

Sites in registry order. Save your city in your profile to sort them by distance.

SiteCityCountrySite status
Florida State University
Coordinator of this site? Confirm its status
TallahasseeUnited StatesUnknown status

This page is information, not medical advice. Discuss any trial with your doctor.