NCT05718947Completed
Ultra-high-field Brain MRI in Multiple Sclerosis
Multiple Sclerosis Lesion Characterization on Ultra-high-field MRI: Comparative Pilot Study of 9.4 Vs 7 Vs 3 Tesla
Source: ClinicalTrials.gov · Last updated 19 Sept 2024
Brief summary (registry, in English)
The MRI scan is one of the most important tools for diagnosing multiple sclerosis (MS) and for monitoring disease progression and medication effects. Increasingly strong MRI magnets (higher field strength) enable us to see abnormalities in the brain in greater detail. On the other hand, it poses challenges because these higher field strength MRIs are more sensitive to disturbances, for example due to motion, including physiological motion such as breathing and swallowing. In current practice, field strengths of up to 3 Tesla are common. The aim of this study is to compare scanning at field strengths of 3 Tesla in 10 MS patients at two different moments (baseline and 6 months) with scanning at field strengths that are higher, namely 7 and 9.4 Tesla, in order to identify the advantages and disadvantages. With the further development of this technique, the investigators may be able to make a better diagnosis in the future and detect subtle changes in the course of the disease more quickly in order to optimize treatments.
- Status (registry)
- Completed
- Study type
- Observational
- Enrollment
- 10 (actual)
- First submitted
- 30 Jan 2023
- Start date
- 12 Sept 2023
- Primary completion date
- 17 Jun 2024
- Lead sponsor
- Zuyderland Medisch Centrum
- Diseases
- Multiple sclerosis
- NCT number
- NCT05718947
What you commit to
- Study type: Observational
- Participants enrolled: 10
- From 12 Sept 2023 to the primary completion date, 17 Jun 2024
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- Not being able to lie flat long enough (for the MRI) because of another medical condition
Other
- Non-compatible implanted material/devices
Who the study is looking for
- Relapsing remitting MS patients (according to the 2017 McDonald criteria)
- Age 18-65 years
- New brain MRI lesion in the past 15 months.
Age in the registry: 18 years to 65 years · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Zuyderland MC Coordinator of this site? Confirm its status | Geleen | Netherlands | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.