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NCT05718947Completed

Ultra-high-field Brain MRI in Multiple Sclerosis

Multiple Sclerosis Lesion Characterization on Ultra-high-field MRI: Comparative Pilot Study of 9.4 Vs 7 Vs 3 Tesla

Source: ClinicalTrials.gov · Last updated 19 Sept 2024

Brief summary (registry, in English)

The MRI scan is one of the most important tools for diagnosing multiple sclerosis (MS) and for monitoring disease progression and medication effects. Increasingly strong MRI magnets (higher field strength) enable us to see abnormalities in the brain in greater detail. On the other hand, it poses challenges because these higher field strength MRIs are more sensitive to disturbances, for example due to motion, including physiological motion such as breathing and swallowing. In current practice, field strengths of up to 3 Tesla are common. The aim of this study is to compare scanning at field strengths of 3 Tesla in 10 MS patients at two different moments (baseline and 6 months) with scanning at field strengths that are higher, namely 7 and 9.4 Tesla, in order to identify the advantages and disadvantages. With the further development of this technique, the investigators may be able to make a better diagnosis in the future and detect subtle changes in the course of the disease more quickly in order to optimize treatments.

Status (registry)
Completed
Study type
Observational
Enrollment
10 (actual)
First submitted
30 Jan 2023
Start date
12 Sept 2023
Primary completion date
17 Jun 2024
Lead sponsor
Zuyderland Medisch Centrum
NCT number
NCT05718947

What you commit to

  • Study type: Observational
  • Participants enrolled: 10
  • From 12 Sept 2023 to the primary completion date, 17 Jun 2024
  • 1 site in 1 country
  • Visits and tests: ask the trial team, the registry does not list them

Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.

Who cannot take part

Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.

Other illness

  • Not being able to lie flat long enough (for the MRI) because of another medical condition

Other

  • Non-compatible implanted material/devices

Who the study is looking for

  • Relapsing remitting MS patients (according to the 2017 McDonald criteria)
  • Age 18-65 years
  • New brain MRI lesion in the past 15 months.

Age in the registry: 18 years to 65 years · Sex: All · Does not accept healthy volunteers

Full criteria on ClinicalTrials.gov

Sites (1)

Sites in registry order. Pick your city on the disease page to sort them by distance.

SiteCityCountrySite status
Zuyderland MC
Coordinator of this site? Confirm its status
GeleenNetherlandsUnknown status

This page is information, not medical advice. Discuss any trial with your doctor.