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NCT05720780Recruiting

Rehabilitation Training With Music-support & Exercise Tolerance in COPD and CRF Patients.

Can Rehabilitation Training With Music-support Increase Exercise Tolerance in Individuals With COPD and CRF Compared to Rehabilitation Training Alone? A Randomized Control Trial.

Source: ClinicalTrials.gov · Last updated 23 Feb 2026

Brief summary (registry, in English)

Therapeutic-rehabilitative interventions supported by music can be considered important resources in many clinical contexts. Some studies report the improvement of psychological (i.e. anxiety) and physiological parameters such for example, dyspnea, blood pressure, quality of life, sleep disturbances, etc. through voice, singing, exercise with wind instruments, and sometimes listening to music. Among the various instruments proposed to support the physical training of COPD patients, music was also tested and, in particular, music as a distracting auditory stimulus (DAS) has been used to increase exercise and physical activity adherence and to reduce the perception of dyspnea in COPD subjects. This randomized controlled trial will compare -in patients with COPD and CRF- the effects of the addiction of music to the training on exercise capacity (possible improvement of endurance and reduction of fatigue and dyspnea) with respect to the usual rehabilitation modality (no music).

Status (registry)
Recruiting
Study type
Interventional
Enrollment
156 (estimated)
First submitted
31 Jan 2023
Start date
26 Jan 2023
Primary completion date
31 Dec 2026
Lead sponsor
Istituti Clinici Scientifici Maugeri SpA
Diseases
COPD
NCT number
NCT05720780

What you commit to

  • Study type: Interventional
  • Planned participants: 156
  • From 26 Jan 2023 to the primary completion date, 31 Dec 2026
  • 6 sites in 1 country
  • Visits and tests: ask the trial team, the registry does not list them

Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.

Who cannot take part

Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.

Prior treatment

  • Pulmonary rehabilitation program in the previous 6 months

Other illness

  • Cognitive impairment (Mini-Mental State Examination Score \< 22)
  • Obstructive sleep apnea syndrome
  • Lung cancer
  • Active microbial infections
  • Neuromuscular, orthopedic, and/or medical conditions that preclude testing

Other

  • Non-invasive ventilation at home
  • Asthma or evidence of bronchodilator response
  • Pulmonary fibrosis

Who the study is looking for

  • Diagnosis of COPD (Forced expiratory volume in 1 second / post-bronchodilator forced vital capacity \< 0.7) without functional reversibility
  • Chronic respiratory failure with stable hypoxia (PaO2 \< 60 mmHg in room air)
  • Long Term Oxygen Therapy (LTOT) for at least 3 months
  • Clinical stability: pH range 7.38-7.42, with no recent exacerbations in the last 7 days and no changes in drug therapy in the previous 7 days

Age in the registry: 40 years to 85 years · Sex: All · Does not accept healthy volunteers

Full criteria on ClinicalTrials.gov

Sites (6)

Sites in registry order. Pick your city on the disease page to sort them by distance.

SiteCityCountrySite status
ICS Maugeri IRCCS, respiratory rehabilitation of the Institute of Bari
Coordinator of this site? Confirm its status
BariItalyNot yet recruiting
ICS Maugeri IRCCS, Respiratory Rehabilitation of the Institute of Lumezzane
Coordinator of this site? Confirm its status
LumezzaneItalyRecruiting
ICS Maugeri IRCCS, respiratory rehabilitation of the Institute of Montescano
Coordinator of this site? Confirm its status
MontescanoItalyRecruiting
ICS Maugeri IRCCS, Respiratory rehabilitation of the Institute of Pavia
Coordinator of this site? Confirm its status
PaviaItalyRecruiting
ICS Maugeri IRCCS, respiratory rehabilitation of the Institute of Telese
Coordinator of this site? Confirm its status
Telese TermeItalyNot yet recruiting
ICS Maugeri IRCCS, Respiratory rehabilitation of the Institute of Tradate
Coordinator of this site? Confirm its status
TradateItalyRecruiting

This page is information, not medical advice. Discuss any trial with your doctor.