NCT05724173Recruiting
Feasibility of the BrainGate2 Neural Interface System in Persons With Tetraplegia
Single Neuron Population Dynamics in Human Speech Motor Cortex for a Speech Prosthesis
Source: ClinicalTrials.gov · Last updated 2 Jun 2026
Brief summary (registry, in English)
The purpose of this study is to obtain preliminary device safety information and demonstrate proof of principle (feasibility) of the ability of people with tetraplegia to control a computer cursor and other assistive devices with their thoughts.
- Status (registry)
- Recruiting
- Study type
- Interventional
- Enrollment
- 3 (estimated)
- First submitted
- 12 Jan 2023
- Start date
- 18 Oct 2023
- Primary completion date
- 31 Jul 2027
- Lead sponsor
- Leigh R. Hochberg, MD, PhD.
- Diseases
- ALS (motor neurone disease)
- NCT number
- NCT05724173
What you commit to
- Study type: Interventional
- Planned participants: 3
- From 18 Oct 2023 to the primary completion date, 31 Jul 2027
- 2 sites in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Chronic oral or intravenous steroids or immunosuppressive therapy
Other illness
- Visual impairment such that extended viewing of a computer monitor would be difficult even with ordinary corrective lenses
- Other serious disease or disorder that could seriously affect ability to participate in the study
- (There are additional exclusion criteria)
Who the study is looking for
- Between 18 and 80 years of age.
- Participants must have a diagnosis of amyotrophic lateral sclerosis (ALS) as verified by a clinical expert in neurologic diseases.
- Participants with a diagnosis of ALS with anarthria, or severe dysarthria with decline in the preceding four months.
- Must be within a three-hour drive of the Study site and geographically stable for at least 15 months after enrollment.
Age in the registry: 18 years to 80 years · Sex: All · Does not accept healthy volunteers
Sites (2)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Massachusetts General Hospital Coordinator of this site? Confirm its status | Boston | United States | Recruiting |
| Stanford University School of Medicine Coordinator of this site? Confirm its status | Stanford | United States | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.