NCT05724992Recruiting
Familial Pancreatic Cancer PROPHilation Program in Italy
Standardised Genetic Profiling of Subjects Belonging to the Italian Multicenter Registry of Prospective Surveillance of Subjects at Genetic Risk of Pancreatic Cancer
Source: ClinicalTrials.gov · Last updated 15 Feb 2023 · Not updated for over 12 months - ask the site whether it is still open
Brief summary (registry, in English)
The goal of the PROPH-ITA Study is to perform genetic testing in family members of pancreatic cancer patients who may have a genetic predisposition. The subjects belong to the Italian Registry of Families At Risk of Pancreatic Cancer (IRFARPC, #NCT04095195). This investigational study will assess the genetic background of subjects with familiarity with pancreatic cancer only. Participants may accept to undergo genetic testing as part of the IRFARPC registry, through a saliva-swab-based 41-gene panel test. Up to 3,000 participants will be enrolled in this study.
- Status (registry)
- Recruiting
- Study type
- Interventional
- Enrollment
- 3000 (estimated)
- First submitted
- 20 Dec 2022
- Start date
- 20 Dec 2022
- Primary completion date
- 20 Dec 2027
- Lead sponsor
- Associazione Italiana per lo Studio del Pancreas
- Diseases
- Pancreatic cancer
- NCT number
- NCT05724992
What you commit to
- Study type: Interventional
- Planned participants: 3000
- From 20 Dec 2022 to the primary completion date, 20 Dec 2027
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other
- \- Already known genetic mutation
Who the study is looking for
- Being enrolled on the IRFARPC registry
- Having familiarity for pancreatic cancer (according to the IRFARPC criteria, Capurso et al. Dig Liv Dis, 2020)
- Willingness to participate in saliva-swab-based genetic testing
Age in the registry: 18 years to 80 years · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Chirurgia generale e del Pancreas Azienda Ospedaliera Universitaria Integrata Coordinator of this site? Confirm its status | Verona | Italy | Recruiting |
Related publications
- Discovering Hereditary Risk Through Surveillance: A Prospective Genetic Analysis of Individuals With Familial Pancreatic Cancer.United European Gastroenterol J · 2026 · PMID 41691430
This page is information, not medical advice. Discuss any trial with your doctor.