NCT05726981Completed
Ultrasound and Cytological Evaluation 3 Years After Radiofrequency Thermal Ablation of Benign Thyroid Nodules : a Prospective Exploratory Cohort of 180 Nodules
Source: ClinicalTrials.gov · Last updated 19 Aug 2026
Brief summary (registry, in English)
There is no scientific data on post-thermal ablation cytological aspects, but treated nodules that grow back significantly after a procedure justify a new cytology in order not to ignore a neoplastic process. The EU-TIRADS classification usually used to stratify the risk of cancer (and to justify a fine needle aspiration biopsy) of thyroid nodules is not validated for nodules treated by thermal ablation (TA) (post-RF nodules). However, these nodules often acquire ultrasound criteria of suspicion making it necessary to develop an ultrasound stratification of the risk of malignancy specific to nodules treated by TA. The objective of this work is to describe the ultrasound and cytological aspects of these treated nodules by performing a systematic assessment at 3 years after thermal ablation including systematic neck ultrasound and fine needle aspiration biopsy. Thus, an ultrasound and cytological atlas (Bethesda classification 2017) of nodules treated by thermal ablation will be constituted.
- Status (registry)
- Completed
- Study type
- Interventional
- Enrollment
- 85 (actual)
- First submitted
- 12 Jan 2023
- Start date
- 29 Jun 2023
- Primary completion date
- 8 Jan 2026
- Lead sponsor
- Assistance Publique - Hôpitaux de Paris
- NCT number
- NCT05726981
What you commit to
- Study type: Interventional
- Participants enrolled: 85
- From 29 Jun 2023 to the primary completion date, 8 Jan 2026
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Previous alcohol use
Other illness
- Persons under forced psychiatric care
Age
- Persons of full age who are under legal protection (guardianship or curatorship)
Other
- Pregnant or breastfeeding women
- Patients on anti-vitamin K anticoagulants
- Patients on direct oral anticoagulants
- Persons deprived of liberty by judicial or administrative decision
- Persons admitted to a health or social institution for purposes other than research
- Persons unable to express their consent
- Persons under a legal protection measure (there can be no derogation for this category)
Who the study is looking for
- Patients \> 18 years old
- Carrier of a benign thyroid nodule that has undergone radiofrequency thermoablation 36 months previously ± 12 months +/- 1 month, whether the nodule is stable, progressing or decreasing in volume during the screening period and/or on the day of inclusion.
- Obtaining written informed consent
- Affiliation to a social security system (excluding AME)
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Hospital Pitié-Salpêtrière - Department of Thyroid and Endocrine Tumour Pathologies Coordinator of this site? Confirm its status | Paris | France | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.