NCT05734261Recruiting
Forced Oscillations Technique During a Metacholine Test in Children
Interest of Forced Oscillations During a Methacholine Test in Children
Source: ClinicalTrials.gov · Last updated 11 Sept 2026
Brief summary (registry, in English)
Asthma is the most common chronic lung disease in children. It affects more than 1 in 10 children in France. The methacholine bronchial challenge test (MBT) is indicated to assess the probability of asthma suggested by clinical symptoms by measuring the forced expiratory volume in one second (FEV1), after inhalation of a cumulative dose of methacholine. In children, the measurement of FEV1 requires a high level of cooperation from the child, which can be the source of false negatives or no result if this is not obtained. The objective of this study is to evaluate if the measurement of the respiratory function by the forced oscillations technique, allows to predict the variation of the FEV1 obtained
- Status (registry)
- Recruiting
- Study type
- Interventional
- Enrollment
- 112 (estimated)
- First submitted
- 2 Feb 2023
- Start date
- Sept 2023
- Primary completion date
- Feb 2027
- Lead sponsor
- University Hospital, Montpellier
- Diseases
- Asthma
- NCT number
- NCT05734261
What you commit to
- Study type: Interventional
- Planned participants: 112
- From Sept 2023 to the primary completion date, Feb 2027
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Upper or lower respiratory tract infections within 3 weeks prior to inclusion
Other illness
- Epilepsy under treatment
Other
- Use of a short-acting beta-adrenergic bronchodilator within the last 6 hours or anticholinergic bronchodilator within the last 12 hours
- Use of a long-acting beta-adrenergic bronchodilator (licensed for use in children) in the past 36 hours
- Subject's participation in another interventional study that may alter respiratory function
- Patient unable to give consent, vulnerable
Who the study is looking for
- Age between 6 and 16 years
- FEV1 \> 60%
- Child referred to the pulmonary function test laboratory for a non-specific bronchial hyperactivity test with methacholine
- Child under treatment with inhaled corticosteroids stopped for at least 3 weeks
- Oral consent from the child and at least one of the legal representatives
- Child affiliated or benefiting from a social security plan
Age in the registry: 6 years to 16 years · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| CHU de Montpellier Coordinator of this site? Confirm its status | Montpellier | France | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.