NCT05738967Completed
Transdiagnostic Behavioral Therapy for Anxiety and Depression in Autistic Adolescents
Source: ClinicalTrials.gov · Last updated 23 Sept 2026
Brief summary (registry, in English)
This study tests the effectiveness of a transdiagnostic cognitive behavioral therapy for autistic youth with anxiety and/or depression.
- Status (registry)
- Completed
- Study type
- Interventional
- Enrollment
- 47 (actual)
- First submitted
- 8 Feb 2023
- Start date
- 15 Mar 2023
- Primary completion date
- 31 May 2025
- Lead sponsor
- Baylor College of Medicine
- Diseases
- Autism
- NCT number
- NCT05738967
What you commit to
- Study type: Interventional
- Participants enrolled: 47
- From 15 Mar 2023 to the primary completion date, 31 May 2025
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- The child is receiving concurrent psychotherapy for anxiety/depression.
- The child has initiated psychotropic medications within 12 weeks of assessments (or 4 weeks for stimulants/benzodiazepines) or during therapy, and/or has changed dosage of psychotropic medication within 6 weeks of assessment (or 2 weeks for stimulants/benzodiazepines) or during therapy.
Other illness
- The child has a diagnosis of psychotic disorder and/or conduct disorder.
Other
- The child has severe suicidal/homicidal ideation and/or self-injury requiring immediate intervention and/or a higher level of care.
- The child has limited verbal communication abilities.
Who the study is looking for
- Child is between the ages of 10-17 at consent/assent.
- The child meets criteria for autism spectrum disorder using evidence-based assessment approaches (e.g., Autism Diagnostic Observation Schedule-Second Edition; Childhood Autism Rating Scale-Second Edition).
- The child meets criteria for clinically significant anxiety and/or depression symptoms based on elevated scores on the Pediatric Anxiety Rating Scale modified for Autism Spectrum Disorder (\>11) and/or the Children's Depression Rating Scale-Revised (\>39).
- Anxiety/depressive disorder is the primary presenting problem as determined by administration of the Mini International Neuropsychiatric Interview
- One parent/guardian is able and willing to participate.
- The parent/guardian is 18 years or older.
- Both parent and child can read and/or understand English.
- Both parent and child reside in Texas.
Age in the registry: 10 years to 17 years · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Baylor Psychiatry Clinic Coordinator of this site? Confirm its status | Houston | United States | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.