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NCT05738967Completed

Transdiagnostic Behavioral Therapy for Anxiety and Depression in Autistic Adolescents

Source: ClinicalTrials.gov · Last updated 23 Sept 2026

Brief summary (registry, in English)

This study tests the effectiveness of a transdiagnostic cognitive behavioral therapy for autistic youth with anxiety and/or depression.

Status (registry)
Completed
Study type
Interventional
Enrollment
47 (actual)
First submitted
8 Feb 2023
Start date
15 Mar 2023
Primary completion date
31 May 2025
Lead sponsor
Baylor College of Medicine
Diseases
Autism
NCT number
NCT05738967

What you commit to

  • Study type: Interventional
  • Participants enrolled: 47
  • From 15 Mar 2023 to the primary completion date, 31 May 2025
  • 1 site in 1 country
  • Visits and tests: ask the trial team, the registry does not list them

Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.

Who cannot take part

Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.

Prior treatment

  • The child is receiving concurrent psychotherapy for anxiety/depression.
  • The child has initiated psychotropic medications within 12 weeks of assessments (or 4 weeks for stimulants/benzodiazepines) or during therapy, and/or has changed dosage of psychotropic medication within 6 weeks of assessment (or 2 weeks for stimulants/benzodiazepines) or during therapy.

Other illness

  • The child has a diagnosis of psychotic disorder and/or conduct disorder.

Other

  • The child has severe suicidal/homicidal ideation and/or self-injury requiring immediate intervention and/or a higher level of care.
  • The child has limited verbal communication abilities.

Who the study is looking for

  • Child is between the ages of 10-17 at consent/assent.
  • The child meets criteria for autism spectrum disorder using evidence-based assessment approaches (e.g., Autism Diagnostic Observation Schedule-Second Edition; Childhood Autism Rating Scale-Second Edition).
  • The child meets criteria for clinically significant anxiety and/or depression symptoms based on elevated scores on the Pediatric Anxiety Rating Scale modified for Autism Spectrum Disorder (\>11) and/or the Children's Depression Rating Scale-Revised (\>39).
  • Anxiety/depressive disorder is the primary presenting problem as determined by administration of the Mini International Neuropsychiatric Interview
  • One parent/guardian is able and willing to participate.
  • The parent/guardian is 18 years or older.
  • Both parent and child can read and/or understand English.
  • Both parent and child reside in Texas.

Age in the registry: 10 years to 17 years · Sex: All · Does not accept healthy volunteers

Full criteria on ClinicalTrials.gov

Sites (1)

Sites in registry order. Pick your city on the disease page to sort them by distance.

SiteCityCountrySite status
Baylor Psychiatry Clinic
Coordinator of this site? Confirm its status
HoustonUnited StatesUnknown status

This page is information, not medical advice. Discuss any trial with your doctor.