NCT05740540Active, not recruiting
Implant for Walking After Stroke
Customizable Cooperative Multi-joint Control to Enhance Walking Mobility After Stroke
Source: ClinicalTrials.gov · Last updated 21 Aug 2026
Brief summary (registry, in English)
This is a device study that will evaluate the effect of an implanted stimulator on improving walking in stroke survivors. There are two phases in the study: 1) Screening - this phase determines if the individual is a good candidate to receive an implanted system, 2) Implantation, controller development, and evaluation - this phase includes installing the device and setting the individual up for home use, creating advanced controllers for walking and evaluating the effect of the device over several months.
- Status (registry)
- Active, not recruiting
- Study type
- Interventional
- Enrollment
- 6 (estimated)
- First submitted
- 18 Jan 2023
- Start date
- May 2023
- Primary completion date
- Jun 2027
- Lead sponsor
- MetroHealth Medical Center
- Diseases
- Stroke
- NCT number
- NCT05740540
What you commit to
- Study type: Interventional
- Planned participants: 6
- From May 2023 to the primary completion date, Jun 2027
- 2 sites in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- History of spontaneous fractures or other evidence of excessively low bone density
- Medical complications (cardiac abnormalities, skin breakdowns, uncontrolled seizures, immunological/pulmonary/renal/circulatory compromise, additional neurologic conditions etc.)
- Cardiovascular or pulmonary disease
- Uncontrolled diabetes or hypertension
- Presence of a demand pacemaker or cardiac defibrillator
- Complications of stroke that result in an increased risk of falls (apraxia, uncompensated hemineglect, hemianopsia etc.)
- Significant history of repeated falls
- Any other medical or psychological condition that would be a contraindication
Other
- Non-English speaking
- Significant range of motion limitations (lacking hip extension, etc.)
- Acute orthopedic problems (severe scoliosis, joint dislocations, etc.)
- Pregnancy
- Severely impaired cognition and communication
Who the study is looking for
- At least 6-months post stroke
- Age 21 to 75 years old
- Able to ambulate, but does not require the assistance of more than one person
- Walk slower than 0.8m/s during a 10m walk test
- Lower extremity Fugl-Meyer Motor Assessment (FMA) \<= 20
- Reduced peak hip, knee and/or ankle range of motion during stance or swing phases
- Modified Ashworth Scale (MAS) \<= 2 at the above joints during passive flexion and extension
- Innervated and excitable lower extremity and trunk musculature
- Appropriate body habitus (height and weight within acceptable limits as determined by study physician)
- Adequate social support and stability
- Willingness to comply with follow-up procedures
- Neurologically stable as determined by a physician
Age in the registry: 21 years to 75 years · Sex: All · Does not accept healthy volunteers
Sites (2)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Louis Stokes Cleveland Veterans Affairs Medical Center Coordinator of this site? Confirm its status | Cleveland | United States | Unknown status |
| MetroHealth Medical Center Coordinator of this site? Confirm its status | Cleveland | United States | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.