NCT05748028Recruiting
Pain and Autonomic Symptoms in Parkinson's Disease and Atypical Parkinsonisms
Pain and Autonomic Symptoms in Parkinson's Disease and Atypical Parkinsonisms: Identification of Predictive Patterns of Rehabilitation Outcome and Evaluation of the Impact on Quality of Life
Source: ClinicalTrials.gov · Last updated 17 Apr 2026
Brief summary (registry, in English)
The goal of this observational study is to learn about the impact of the different types of pain and of the domains involved in the autonomic disorders of inpatients and outpatients diagnosed with Parkinson disease (PD) and multiple system atrophy (MSA) admitted to Istituti Clinici Scientifici Maugeri Centers. The main aims are: Evaluate the prevalence of pain and characterize it in Parkinson's disease and atypical parkinsonisms (MSA) Evaluate the effect of rehabilitation on pain and autonomic symptoms Evaluate the prevalence of autonomic symptoms in Parkinson's disease and atypical parkinsonisms (MSA) Assess the impact of pain and autonomic symptoms on quality of life. Participants will perform neurological examination, rehabilitation program and clinical scales. Researchers will compare the two groups of patients (PD and MSA) and the effect of the rehabilitation on pain, autonomic symptoms and quality of life.
- Status (registry)
- Recruiting
- Study type
- Observational
- Enrollment
- 280 (estimated)
- First submitted
- 26 Jan 2023
- Start date
- 15 Jun 2019
- Primary completion date
- 30 Sept 2026
- Lead sponsor
- Istituti Clinici Scientifici Maugeri SpA
- Diseases
- Parkinson disease
- NCT number
- NCT05748028
What you commit to
- Study type: Observational
- Planned participants: 280
- From 15 Jun 2019 to the primary completion date, 30 Sept 2026
- 9 sites in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- assumption of potentially neurotoxic drugs
Other illness
- diabetes mellitus
Other
- vascular or pharmacological parkinsonism
- hepatic or renal dysmetabolism,
- hypothyroidism or hyperthyroidism
Who the study is looking for
- Clinical diagnosis of Parkinson's Disease or Multiple System Atrophy according to current international criteria (Gilman S et al, 2008; Postuma RB et al. 2015).
- Mini-Mental State Examination score at least 10
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (9)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| ICS Maugeri - Castelgoffredo Coordinator of this site? Confirm its status | Castel Goffredo | Italy | Recruiting |
| ICS Maugeri - Lumezzane Coordinator of this site? Confirm its status | Lumezzane | Italy | Recruiting |
| ICS Maugeri - Milano Coordinator of this site? Confirm its status | Milan | Italy | Recruiting |
| ICS Maugeri - Mistretta Coordinator of this site? Confirm its status | Mistretta | Italy | Recruiting |
| ICS Maugeri - Montescano Coordinator of this site? Confirm its status | Montescano | Italy | Recruiting |
| ICS Maugeri - Pavia Coordinator of this site? Confirm its status | Pavia | Italy | Recruiting |
| ICS Maugeri - Pavia Boezio Coordinator of this site? Confirm its status | Pavia | Italy | Recruiting |
| ICS Maugeri - IRCCS of Telese Terme Coordinator of this site? Confirm its status | Telese Terme | Italy | Recruiting |
| ICS Maugeri - Veruno Coordinator of this site? Confirm its status | Veruno | Italy | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.