NCT05750173Completed
The EASE-IT CT Registry
Pre-procedural Assessment of Coronary Artery Disease in Patients Undergoing Transcatheter Aortic Valve Implantation (TAVI) - Comparision of Pre-TAVI CTA vs. Pre-TAVI ICA
Source: ClinicalTrials.gov · Last updated 30 Mar 2026
Brief summary (registry, in English)
ICA is not always required for a pre-TAVI workup of octogenarians and can be substituted by CTA resulting in a streamlined pre-procedural workup of patients without compromising patient safety.
- Status (registry)
- Completed
- Study type
- Observational
- Enrollment
- 150 (actual)
- First submitted
- 8 Dec 2022
- Start date
- 1 Sept 2023
- Primary completion date
- 24 Mar 2026
- Lead sponsor
- Institut für Pharmakologie und Präventive Medizin
- Diseases
- Coronary artery disease
- NCT number
- NCT05750173
What you commit to
- Study type: Observational
- Participants enrolled: 150
- From 1 Sept 2023 to the primary completion date, 24 Mar 2026
- 6 sites in 2 countries
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study design.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Any prior coronary revascularization / prior aortic valve replacement
- Any prior coronary revascularization / prior aortic valve replacement
Other
- investigational CTA-only Cohort
- Patients with already diagnosed proximal stenosis of the left anterior descending artery (LAD) OR the left main coronary artery (LM) ≥50%
- Life expectancy below 12 months
- Lack of informed consent / data protection statement
- CTA+ICA control Cohort
- Patients diagnosed with proximal stenosis of the left anterior descending artery (LAD) OR the left main coronary artery (LM) ≥50% already at baseline
- Life expectancy below 12 months
- Lack of informed consent / data protection statement
Who the study is looking for
- Investigational CTA-only Cohort
- Consecutive adult patients ≥ 75 years
- Consecutive patients with severe AS (symptomatic or asymptomatic) with a guideline-based indication to undergo implantation of a transcatheter heart valve of the SAPIEN family
- Ability to undergo CTA
- Patient is scheduled to undergo a 30 Day and 3 Months follow-up
- CTA+ICA control Cohort
- Consecutive adult patients ≥ 75 years
- Consecutive patients underwent implantation of a transcatheter heart valve of the SAPIEN family because of severe aortic stenosis
- Ability to undergo CTA and ICA
Age in the registry: 75 years to - · Sex: All
Sites (6)
Sites in registry order. Save your city in your profile to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Universitätsklinik für Innere Medizin III - Kardiologie und Angiologie Coordinator of this site? Confirm its status | Innsbruck | Austria | Unknown status |
| University Clinic St. Pölten Coordinator of this site? Confirm its status | Sankt Pölten | Austria | Unknown status |
| Medical University of Vienna Coordinator of this site? Confirm its status | Vienna | Austria | Unknown status |
| Klinik Floridsdorf Coordinator of this site? Confirm its status | Vienna | Austria | Unknown status |
| University Hospital Bochum / HDZ NRW Coordinator of this site? Confirm its status | Bad Oeynhausen | Germany | Unknown status |
| University Hospital of the Bergmannsheil gGmbH Coordinator of this site? Confirm its status | Bochum | Germany | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.