NCT05750576Completed
Impact of ECMO Cannula Chlorhexidine-impregnated Dressings to Decrease Extracorporeal Membrane Oxygenation-cannula Related Infection Rate
Source: ClinicalTrials.gov · Last updated 24 Nov 2025
Brief summary (registry, in English)
The Dressing-ECMO trial is a prospective, open-label, multicenter, controlled trial randomizing patients who received percutaneous ECMO to cannula chlorhexidine-impregnated dressing vs standard dressing. The study goal is to determine if cannula chlorhexidine-impregnated dressings can reduce the number of cannula major-related infections with or without bloodstream infection
- Status (registry)
- Completed
- Study type
- Interventional
- Enrollment
- 270 (actual)
- First submitted
- 19 Jan 2023
- Start date
- 15 Jun 2023
- Primary completion date
- 20 Jun 2025
- Lead sponsor
- Assistance Publique - Hôpitaux de Paris
- NCT number
- NCT05750576
What you commit to
- Study type: Interventional
- Participants enrolled: 270
- From 15 Jun 2023 to the primary completion date, 20 Jun 2025
- 6 sites in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Surgical (i.e. non percutaneous) cannulation
Other illness
- Known allergy to chlorhexidine
Age
- Age \<18 years
Other
- Initiation of ECMO for more than 24 hours
- Patient moribund on day of randomization, SAPS II \>90
- Antibiotic prophylaxis at ECMO cannulation
Who the study is looking for
- Patients with cardiogenic shock or refractory acute respiratory distress syndrome ECMO VA or VV ECMO for less than 24 hours.
- ECMO duration \> 48 hours
- Obtained written informed consent from the trusted person or family member/relative. Depending on the emergency consent, randomization may take place and consent of the trusted person/relative/family will be obtained as soon as possible. The patient will be asked to give his/her consent for the continuation of the trial when hid/her condition will allow.
- Affiliation to a social security system (excluding state medical aid)
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (6)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| CHU Besancon - Hopital Jean Minjoz Coordinator of this site? Confirm its status | Besançon | France | Unknown status |
| CH Sud Francilien Coordinator of this site? Confirm its status | Corbeil-Essonnes | France | Unknown status |
| Hopital Henri Mondor Coordinator of this site? Confirm its status | Créteil | France | Unknown status |
| CHRU Nancy Hopitaux de Brabois Coordinator of this site? Confirm its status | Nancy | France | Unknown status |
| Hopital Pitie-Salpetriere Coordinator of this site? Confirm its status | Paris | France | Unknown status |
| Hopital Foch Coordinator of this site? Confirm its status | Suresnes | France | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.