NCT05754814Completed
SUper-Resolution Ultrasound Imaging of Erythrocytes (SURE) in Normal and Malignant Lymph Nodes
Source: ClinicalTrials.gov · Last updated 8 May 2026
Brief summary (registry, in English)
The goal of this observational study is to visualize the small vessels in normal and cancerous lymph nodes on the neck with a new ultrasound technique. The main questions it aims to answer are: * Is it possible to visualize the network of the smallest vessels in lymph nodes on the neck? * Is it possible to distinguish between healthy and cancerous lymph nodes using different parameters? The participants will have 1 lymph nodes ultrasound scanned with a standard ultrasound technique and the new technique.
- Status (registry)
- Completed
- Study type
- Observational
- Enrollment
- 20 (actual)
- First submitted
- 26 Jan 2023
- Start date
- 28 Jun 2022
- Primary completion date
- 1 Apr 2026
- Lead sponsor
- Copenhagen University Hospital, Rigshospitalet
- Diseases
- Head and neck cancer
- NCT number
- NCT05754814
What you commit to
- Study type: Observational
- Participants enrolled: 20
- From 28 Jun 2022 to the primary completion date, 1 Apr 2026
- 2 sites in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- Dementia
- Ongoing or recent (within the last 4 weeks) infectious disease (bacterial, viral, fungal, or protozoal) which may give rise to reactive lymph nodes
- Diseases that cause lymphadenopathy: Some chronic infectious diseases (HIV, Tuberculosis, Hepatitis B), Systemic diseases (rheumatoid arthritis, systemic lupus erythematosus, sarcoidosis, other rare systemic diseases\*), Primary adrenal insufficiency (Addison´s disease), Leukemia, Lymphoma or other cancers (besides the type of cancer the participant is being examined for at the Department of Otorhinolaryngology, Head and Neck Surgery \& Audiology, Rigshospitalet)
- Drugs that cause lymphadenopathy: Antibiotics (Cephalosporins, Penicillin, Sulfonamides), Antiepileptics (Carbamazepine, Ethosuximide, Lamotrigine, Phenytoin, Primidone), Antihypertensives (Atenolol, Captopril, Hydralazine), Other (Allopurinol, Imatinib)
- Castleman's disease, Kikuchi's disease, Kawasaki disease, Inflammatory pseudotumor, Amyloidosis, Kimura disease, Rosai-Dorfman disease, IgG4-related disease, Still's disease, dermatomyositis, Churg-Strauss, histiocytosis, chronic granulomatous diseases, Autoimmune lymphoproliferative syndrome, lipid storage diseases.
Other
- Pregnancy
- Physique making ultrasound scanning difficult
Who the study is looking for
- Participants must be 18 years or older, at the time of signing the informed consent
- Participants who can lie still for 1 minute
- Capable of giving signed informed consent
- Participants who are overtly healthy as determined by medical history
- Participants who have a superficial lymph node laterally on the neck with a normal appearance on standard B-mode ultrasound available for SURE imaging
- Participants who, besides their untreated head and neck cancer or lymphoma, are overtly healthy as determined by medical evaluation and medical history
- Participants with lymphoma or head and neck cancer and lymph node metastasis verified by a biopsy or surgical excision.
- Participants who have superficial lymph nodes laterally on the neck
Age in the registry: 18 years to - · Sex: All · Accepts healthy volunteers
Sites (2)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Rigshospitalet Coordinator of this site? Confirm its status | Copenhagen | Denmark | Unknown status |
| Technical University of Denmark Coordinator of this site? Confirm its status | Kongens Lyngby | Denmark | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.