Sign in

NCT05756127Active, not recruiting

Future Innovations in Novel Detection of Heart Failure FIND-HF

Predicting Incident Heart Failure from Population-based Nationwide Electronic Health Records: Protocol for a Model Development and Validation Study

Source: ClinicalTrials.gov · Last updated 30 Mar 2025

Brief summary (registry, in English)

Heart failure (HF) is increasingly common and associated with excess morbidity, mortality and healthcare costs. New medications are now available which can alter the disease trajectory and reduce clinical events. However, many cases of HF remain undetected until presentation with more advanced symptoms, often requiring hospitalisation. Earlier identification and treatment of HF could reduce downstream healthcare impact, but predicting HF incidence is challenging due to the complexity and varying course of HF. The investigators will use routinely collected hospital-linked primary care data and focus on the use of artificial intelligence methods to develop and validate a prediction model for incident HF. Using clinical factors readily accessible in primary care, the investigators will provide a method for the identification of individuals in the community who are at risk of HF, as well as when incident HF will occur in those at risk, thus accelerating research assessing technologies for the improvement of risk prediction, and the targeting of high-risk individuals for preventive measures and screening.

Status (registry)
Active, not recruiting
Study type
Observational
Enrollment
14000 (estimated)
First submitted
31 Jan 2023
Start date
1 Apr 2023
Primary completion date
31 Dec 2025
Lead sponsor
University of Leeds
NCT number
NCT05756127

What you commit to

  • Study type: Observational
  • Planned participants: 14000
  • From 1 Apr 2023 to the primary completion date, 31 Dec 2025
  • 1 site in 1 country
  • Visits and tests: ask the trial team, the registry does not list them

Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.

Who cannot take part

Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.

Other

  • \-

Who the study is looking for

  • Aged 16 years and older
  • No history of heart failure
  • A minimum of one year follow up

Age in the registry: 16 years to 120 years · Sex: All · Does not accept healthy volunteers

Full criteria on ClinicalTrials.gov

Sites (1)

Sites in registry order. Pick your city on the disease page to sort them by distance.

SiteCityCountrySite status
University of Leeds
Coordinator of this site? Confirm its status
LeedsUnited KingdomUnknown status

This page is information, not medical advice. Discuss any trial with your doctor.