NCT05756257Recruiting
Blood Pressure Variability and Ischemic Stroke Outcome
Source: ClinicalTrials.gov · Last updated 28 Sept 2026
Brief summary (registry, in English)
The goal of this observational study is to evaluate the role of blood pressure (BPV) variability in patients suffering from acute ischemic stroke. The main questions it aims to answer are: 1. To determine the association of BPV with functional/cognitive outcome after ischemic stroke. 2. To determine a pathophysiologic mechanism of BPV's deleterious effect on functional outcome. 3. To evaluate potential treatment targets to pharmacologically reduce BPV after ischemic stroke.
- Status (registry)
- Recruiting
- Study type
- Observational
- Enrollment
- 150 (estimated)
- First submitted
- 15 Feb 2023
- Start date
- 15 Jul 2024
- Primary completion date
- 15 Jul 2027
- Lead sponsor
- Yale University
- Diseases
- Stroke
- NCT number
- NCT05756257
What you commit to
- Study type: Observational
- Planned participants: 150
- From 15 Jul 2024 to the primary completion date, 15 Jul 2027
- 3 sites in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other
- Pre-morbid mRS ≥3
- Predicted hospital system admission \<72 hours
- Pacemaker or other MRI contraindications per American College of Radiology guidelines
Who the study is looking for
- Ischemic stroke according to the American Heart Association (AHA) definition and either:
- CT or MRI showing ischemic stroke in the anterior circulation (frontal, parietal or superior temporal lobes), or
- Occlusion of the internal carotid, middle cerebral or anterior cerebral arteries on computed tomography angiography (CTA) or magnetic resonance angiography (MRA)
- Onset of ischemic stroke within 48 hours and able to get baseline pMRI within 72 hours of arrival
- 4\) NIH Stroke Scale ≥ 4 at time of enrollment
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (3)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Massachusetts General Hospital Coordinator of this site? Confirm its status | Boston | United States | Recruiting |
| University of Chicago Medical Center Coordinator of this site? Confirm its status | Chicago | United States | Recruiting |
| Yale New Haven Hospital Coordinator of this site? Confirm its status | New Haven | United States | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.