NCT05758688RecruitingPhase 2
PROton Therapy for Post Surgical Treatment of GYNecologic Cancer
Adjuvant Proton Whole Pelvis Radiation Therapy for Treatment of Post-Surgical Gynecologic Cancers
Source: ClinicalTrials.gov · Last updated 17 Sept 2026
Brief summary (registry, in English)
This is a single institution, multi-center, Phase II, single-arm study, using Whole Pelvis (WP) Pencil Beam Scanning Proton Radiation (PBS PRT) in the post-surgical, adjuvant setting for definitive treatment of gynecologic cancers. The purpose of this study is to estimate rate of acute clinician-reported gastrointestinal (GI) toxicity using WP PBS PRT in the definitive treatment of gynecologic cancers in the post-surgical, adjuvant setting.
- Status (registry)
- Recruiting
- Phase (registry)
- Phase 2
- Study type
- Interventional
- Enrollment
- 25 (estimated)
- First submitted
- 24 Jan 2023
- Start date
- 6 Nov 2023
- Primary completion date
- Nov 2026
- Lead sponsor
- Abramson Cancer Center at Penn Medicine
- Diseases
- Endometrial cancer, Cervical cancer
- NCT number
- NCT05758688
What you commit to
- Study type: Interventional · Phase 2
- Planned participants: 25
- From 6 Nov 2023 to the primary completion date, Nov 2026
- 3 sites in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Prior course of pelvic radiation
Other illness
- Metastatic disease outside of the pelvis
- Active inflammatory bowel disease
Other
- Incapacity to provide informed consent
Who the study is looking for
- Histologically confirmed cervical or endometrial cancer
- Indication for adjuvant whole pelvic radiation therapy, with or without systemic therapy
- Age of 18 years or older
- Written informed consent
- ECOG of 0-2 within 3 months of enrolling
Age in the registry: 18 years to - · Sex: Female · Does not accept healthy volunteers
Sites (3)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Lancaster General Health - Ann B. Barshinger Cancer Institute Coordinator of this site? Confirm its status | Lancaster | United States | Recruiting |
| University of Pennsylvania Coordinator of this site? Confirm its status | Philadelphia | United States | Recruiting |
| Virtua Health Coordinator of this site? Confirm its status | Voorhees Township | United States | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.