NCT05760846Recruiting
Bimanual Motor Skill Learning in Acute Stroke
Exploring the Neural Substrates of Proximal and Distal Bimanual Motor Skill Learning Through Robotics and Multimodal Brain Imaging
Source: ClinicalTrials.gov · Last updated 12 Aug 2026
Brief summary (registry, in English)
The subacute phase of stroke provides a window into how a lesion perturbs sensorimotor functions prior to reorganisation driven by plasticity and neurorehabilitation. The recovery from motor impairment has been extensively studied, but it is currently unknown whether motor skill learning (MSkL) is enhanced or impaired during acute stroke, especially bimanual motor skill learning (bim-MSkL), which likely requires more motor-attentional-cognitive resources than unimanual MSkL. The goals of this project are: to determine the neural substrates critical to achieve proximal and distal bimanual motor skill learning (bim-MSkL) by specifying whether (sub)acute stroke to different brain areas (cortical and subcortical) induce specific deficits in bimanual and/or distal bim-MSkL, which behavioral components are involved in bim-MSkL, and whether damage to the motor, sensory and inter-hemispheric pathways specifically impairs proximal and/or distal bim-MSkL.
- Status (registry)
- Recruiting
- Study type
- Interventional
- Enrollment
- 160 (estimated)
- First submitted
- 22 Feb 2023
- Start date
- 17 Apr 2023
- Primary completion date
- Mar 2028
- Lead sponsor
- University Hospital of Mont-Godinne
- Diseases
- Stroke
- NCT number
- NCT05760846
What you commit to
- Study type: Interventional
- Planned participants: 160
- From 17 Apr 2023 to the primary completion date, Mar 2028
- 2 sites in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study design.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- drug/alcohol abuse
- medical history with a previous stroke / relevant neurological deficit
- drug/alcohol abuse
Other illness
- multiple strokes / dementia / psychiatric condition
- HEALTHY INDIVIDUALS:
- psychiatric condition/ dementia
Other
- " classical " contre-indication to MRI (non-MR-compatible pacemaker, pregnancy, non-MR-compatible implanted devices, claustrophobia, etc ...)
- difficulty in understanding or executing commands
- severe aphasia / cognitive deficits interfering with study
- inability to complete the tasks (i.e. full paralysis of the arm)
Who the study is looking for
- acute stroke (\< 21 days)
- aged 18-90 years
- with a demonstrated stroke (ischemic or hemorrhagic) lesion on brain imaging
- 18-90 years
Criteria the registry did not label
- ACUTE STROKE PATIENTS:
Age in the registry: 18 years to 90 years · Sex: All · Accepts healthy volunteers
Sites (2)
Sites in registry order. Save your city in your profile to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Chu Ucl Namur Coordinator of this site? Confirm its status | Yvoir | Belgium | Recruiting |
| University Hospital CHU Dinant Godinne UCL Coordinator of this site? Confirm its status | Yvoir | Belgium | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.