NCT05761067Recruiting
STICH-3.0 International Trial Consortium
The CABG or PCI in Patients With Ischemic Cardiomyopathy (STICH) 3.0 International Trial Consortium
Source: ClinicalTrials.gov · Last updated 25 Sept 2024 · Not updated for over 12 months - ask the site whether it is still open
Brief summary (registry, in English)
The primary objective of the STICH 3.0 Study is to determine whether CABG is superior to PCI in terms of all-cause mortality at 5 years in patients with severe CAD and iLVSD. Individual patient data from similar national RCTs independently powered for different efficacy endpoints will be pooled, harmonized, and analyzed. The primary endpoint is all-cause mortality.
- Status (registry)
- Recruiting
- Study type
- Interventional
- Enrollment
- 2800 (estimated)
- First submitted
- 23 Jan 2023
- Start date
- 14 Sept 2022
- Primary completion date
- 14 Sept 2029
- Lead sponsor
- Vastra Gotaland Region
- Diseases
- Heart failure, Coronary artery disease
- NCT number
- NCT05761067
What you commit to
- Study type: Interventional
- Planned participants: 2800
- From 14 Sept 2022 to the primary completion date, 14 Sept 2029
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Decompensated heart failure requiring inotropic/adrenergic support, invasive or non-invasive ventilation or intra-aortic balloon pump/ ventricular assist device therapy less than 48 hours prior to randomization;
Other illness
- Valvular heart disease or any other cardiac conditions (e.g. LV aneurysm) indicating the need for surgical repair/replacement;
- Prohibitive bleeding risk or clinical scenario mandating avoidance of long-term dual antiplatelet therapy;
Other
- Pregnancy;
- Circumstances likely to lead to poor treatment adherence;
- STEMI within 72 hours;
- PCI within 3 months.
Who the study is looking for
- Age \>18 years
- LVEF ≤40%
- Extensive coronary artery disease (typically defined as a British Cardiovascular Intervention Society jeopardy score of ≥6, on a scale from 0 to 12, with higher scores indicating greater extent of disease).
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Dep of Cardiology, Sahlgrenska University Hospital Coordinator of this site? Confirm its status | Gothenburg | Sweden | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.