NCT05762653Completed
Morphological Pancreatic Features in Diabetes Mellitus Type 2
Morphological Features of the Pancreas in Patients With Type 2 Diabetes Mellitus: Correlation With Clinical Features of the Disease.
Source: ClinicalTrials.gov · Last updated 22 Sept 2026
Brief summary (registry, in English)
Hypothesis: Type 2 diabetes mellitus is associated with pancreatic fibrosis that can be evaluated by minimally invasive imaging techniques. That fibrosis is associated with alteration of exocrine pancreatic function, defined as a reduced secretion of pancreatic enzymes and the development of nutritional deficiencies. To test that hypothesis, a prospective, observational, cross-sectional, comparative, case-control study has been designed. Pancreatic fibrosis will be evaluated by endoscopic ultrasound and quantitative elastography in cases (type-2 diabetes) and age-gender-matched controls without diabetes. Pancreatic function will be explored by fecal elastase test and nutritional evaluation. Calculated sample size is 94 patients (47 cases and 47 controls). Study period is 2 years.
- Status (registry)
- Completed
- Study type
- Observational
- Enrollment
- 94 (actual)
- First submitted
- 5 Jul 2022
- Start date
- 3 Feb 2022
- Primary completion date
- 30 Jun 2023
- Lead sponsor
- Hospital Clinico Universitario de Santiago
- Diseases
- Type 2 diabetes
- NCT number
- NCT05762653
What you commit to
- Study type: Observational
- Participants enrolled: 94
- From 3 Feb 2022 to the primary completion date, 30 Jun 2023
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- History of pancreatic disease or surgery.
- History of upper gastrointestinal surgery.
- Diabetes type other than type-2.
- Severe cardiovascular or respiratory disease.
Other
- Lack of informed consent.
Who the study is looking for
- Patients older than 18 years.
- Undergoing an upper endoscopic ultrasound for any indication other than pancreatic disease.
- Signed informed consent-
- Patients: Previous diagnosis of type-2 diabetes mellitus.
- Controls: Nondiabetic subjects, matched by age, gender, alcohol consumption, and smoking with patients.
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Hospital Clínico Universitario de Santiago Coordinator of this site? Confirm its status | Santiago de Compostela | Spain | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.